@article{fdi:010066163,
  title = {{T}rypanosoma brucei gambiense spliced leader {RNA} is a more specific marker for cure of human {A}frican trypanosomiasis than {T}. b. gambiense {DNA}},
  author = {{I}lboudo, {H}. and {C}amara, {O}. and {R}avel, {S}ophie and {B}ucheton, {B}runo and {L}ejon, {V}eerle and {C}amara, {M}. and {K}abore, {J}. and {J}amonneau, {V}incent and {D}eborggraeve, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}o assess the efficacy of treatment for human {A}frican trypanosomiasis, accurate tests that can discriminate relapse from cure are needed. {W}e report the first data that the spliced leader ({SL}) {RNA} is a more specific marker for cure of human {A}frican trypanosomiasis than parasite {DNA}. {I}n blood samples obtained from 61 patients in whom human {A}frican trypanosomiasis was cured, {SL} {RNA} detection had specificities of 98.4%-100%, while {DNA} detection had a specificity of only 77%. {D}ata from our proof-of-concept study show that {SL} {RNA} detection has high potential as a test of cure.},
  keywords = {human {A}frican trypanosomiasis ; diagnosis ; test of cure ; {RNA} ; specificity ; {GUINEE}},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {212},
  numero = {12},
  pages = {1996--1998},
  ISSN = {0022-1899},
  year = {2015},
  DOI = {10.1093/infdis/jiv337},
  URL = {https://www.documentation.ird.fr/hor/fdi:010066163},
}