@article{fdi:010065500, title = {{E}fficacy of {O}lyset ({R}) {D}uo, a permethrin and pyriproxyfen mixture net against wild pyrethroid-resistant {A}nopheles gambiae s.s. from {C}ote d'{I}voire : an experimental hut trial}, author = {{K}offi, {A}. {A}. and {A}lou, {L}. {P}. {A}. and {D}jenontin, {A}. and {K}abran, {J}. {P}. {K}. and {D}osso, {Y}. and {K}one, {A}. and {M}oiroux, {N}icolas and {P}ennetier, {C}{\'e}dric}, editor = {}, language = {{ENG}}, abstract = {{P}yrethroid resistance in malaria vectors has spread across sub-{S}aharan {A}frica. {A}lternative tools and molecules are urgently needed for effective vector control. {O}ne of the most promising strategies to prevent or delay the development of resistance is to use at least two molecules having unrelated modes of action in combination in the same bed net. {W}e evaluated in experimental huts in {C}ote d'{I}voire, a new polyethylene long-lasting insecticidal net ({LN}) product, {O}lyset ({R}) {D}uo, incorporating permethrin ({PER}) and pyriproxyfen ({PPF}), an insect growth regulator ({IGR}). {PPF} alone or in combination with permethrin had a significant impact on fertility (7-12% reduction relative to control) and no effect on fecundity of wild multi-resistant {A}n. gambiae s.s. {T}hese results triggered crucial research questions on the behaviour of targeted mosquitoes around the {LN}. {T}o maximize the sterilizing effect of {PPF} in the combination, there would be a need for a trade-off between the necessary contact time of the insect with {PPF} and the surface content of the pyrethroid insecticide that is bioavailable and induces excito-repellency.}, keywords = {{A}nopheles gambiae ; pyrethroid insecticide ; resistance ; bed net ; insect growth regulator ; {COTE} {D}'{IVOIRE}}, booktitle = {}, journal = {{P}arasite}, volume = {22}, numero = {}, pages = {28 [8 ]}, ISSN = {1252-607{X}}, year = {2015}, DOI = {10.1051/parasite/2015028}, URL = {https://www.documentation.ird.fr/hor/fdi:010065500}, }