@article{fdi:010065499, title = {{I}nsecticidal and sterilizing effect of {O}lyset {D}uo ({R}), a permethrin and pyriproxyfen mixture net against pyrethroid-susceptible and -resistant strains of {A}nopheles gambiae s.s. : a release-recapture assay in experimental huts}, author = {{D}j{\`e}nontin, {A}. and {A}lou, {L}. {P}. {A}. and {K}offi, {A}. and {Z}ogo, {B}. and {D}uarte, {E}. and {N}'{G}uessan, {R}. and {M}oiroux, {N}icolas and {P}ennetier, {C}{\'e}dric}, editor = {}, language = {{ENG}}, abstract = {{I}n the context of the widespread distribution of pyrethroid resistance among malaria vectors, we did a release-recapture trial in experimental huts to investigate the insecticidal and sterilizing effects of a novel long-lasting net ({LN}), {O}lyset ({R}) {D}uo, incorporating a mixture of permethrin ({PER}) and the insect growth regulator ({IGR}), pyriproxyfen ({PPF}). {A}n {LN} containing {PPF} alone and a classic {O}lyset ({R}) {N}et were tested in parallel as positive controls. {T}he effect of progressive number of holes (6, 30, or 150) that may accrue in nets over time was simulated. {W}e used two laboratory {A}nopheles gambiae s.s. strains: the susceptible {K}isumu strain and the pyrethroid-resistant {VK}-{P}er strain having solely kdr as resistance mechanism. {T}he effect of these nets on the reproductive success of blood-fed females that survived the different {LN}s conditions was recorded. {R}egardless of the mosquito strain, the {LN}s containing {PPF} alone with as many as 30 holes drastically reduced the number of eggs laid by females succeeding in feeding, i.e. fecundity by 98% and egg hatching rate (fertility) by 93% relative to untreated control net. {V}ery few of the resistant females blood fed and survived under the {O}lyset ({R}) {D}uo with similar number of holes (up to 30) but of these few, the inhibition of reproductive success was 100%. {T}here was no evidence that the {O}lyset ({R}) {D}uo {LN} with 150 holes impacted fecundity or fertility of the resistant colony. {T}he efficacy of {O}lyset ({R}) {D}uo is encouraging and clearly illustrates that this new net might be a promising tool for malaria transmission control and resistance management.}, keywords = {{A}nopheles gambiae s.s ; {P}yrethroid ; {R}esistance ; {B}ed net ; {I}nsect growth regulator ; {BENIN}}, booktitle = {}, journal = {{P}arasite}, volume = {22}, numero = {}, pages = {art. 27 [8 p.]}, ISSN = {1252-607{X}}, year = {2015}, DOI = {10.1051/parasite/2015027}, URL = {https://www.documentation.ird.fr/hor/fdi:010065499}, }