%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Paradis, Emmanuel %T Random phylogenies and the distribution of branching times %D 2015 %L fdi:010065494 %G ENG %J Journal of Theoretical Biology %@ 0022-5193 %K Diversity ; Extinction ; LTT plot ; Speciation %M ISI:000365245800005 %P 39-45 %R 10.1016/j.jtbi.2015.09.005 %U https://www.documentation.ird.fr/hor/fdi:010065494 %> https://www.documentation.ird.fr/intranet/publi/2015/12/010065494.pdf %V 387 %W Horizon (IRD) %X Phylogenetic trees reconstructed without fossils have become an important source of information to study evolutionary processes. A widely used method to describe patterns of phylogenetic diversification is known as the lineages-through-time (LTT) plot. Recently, it has been shown that it is possible to predict the distribution of the branching times of a phylogeny, thus making possible to derive a theoretical LTT curve conditioned on diversification parameters. Here, I review some aspects related to this prediction showing how to derive it for any time-dependent model of diversification, as well as calculating a prediction interval around a theoretical LTT curve. The accuracy of the prediction interval was assessed with simulations using fixed or random tree sizes under constant-rate models as well as two models of time-dependent diversification. The prediction intervals were relatively narrower and more accurate for larger trees. The features of this approach are discussed as well as its potential applications. %$ 020