@article{fdi:010065465,
  title = {{U}rban market gardening and rodent-borne pathogenic leptospira in arid zones : a case study in {N}iamey, {N}iger},
  author = {{D}obigny, {G}authier and {G}arba, {M}. and {T}atard, {C}. and {L}oiseau, {A}. and {G}alan, {M}. and {K}adaour{\'e}, {I}. and {R}ossi, {J}. {P}. and {P}icardeau, {M}. and {B}ertherat, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{L}eptospirosis essentially affects human following contact with rodent urine-contaminated water. {A}s such, it was mainly found associated with rice culture, recreational activities and flooding. {T}his is also the reason why it has mainly been investigated in temperate as well as warm and humid regions, while arid zones have been only very occasionally monitored for this disease. {I}n particular, data for {W}est {A}frican countries are extremely scarce. {H}ere, we took advantage of an extensive survey of urban rodents in {N}iamey, {N}iger, in order to look for rodent-borne pathogenic {L}eptospira species presence and distribution across the city. {T}o do so, we used high throughput bacterial 16{S}-based metabarcoding, lip{L}32 gene-targeting {RT}-{PCR}, rrs gene sequencing and {VNTR} typing as well as {GIS}-based multivariate spatial analysis. {O}ur results show that leptospires seem absent from the core city where usual {L}eptospira reservoir rodent species (namely {R}. rattus and {M}. natalensis) are yet abundant. {O}n the contrary, {L}. kirschneri was detected in {A}rvicanthis niloticus and {C}ricetomys gambianus, two rodent species that are restricted to irrigated cultures within the city. {M}oreover, the {VNTR} profiles showed that rodent-borne leptospires in {N}iamey belong to previously undescribed serovars. {A}ltogether, our study points towards the importance of market gardening in maintain and circulation of leptospirosis within {S}ahelian cities. {I}n {A}frica, irrigated urban agriculture constitutes a pivotal source of food supply, especially in the context of the ongoing extensive urbanization of the continent. {W}ith this in mind, we speculate that leptospirosis may represent a zoonotic disease of concern also in arid regions that would deserve to be more rigorously surveyed, especially in urban agricultural settings.},
  keywords = {{NIGER} ; {NIAMEY} ; {ZONE} {ARIDE}},
  booktitle = {},
  journal = {{PL}o{S} {N}eglected {T}ropical {D}iseases},
  volume = {9},
  numero = {10},
  pages = {e0004097 [15 p.]},
  ISSN = {1935-2735},
  year = {2015},
  DOI = {10.1371/journal.pntd.0004097},
  URL = {https://www.documentation.ird.fr/hor/fdi:010065465},
}