%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Feng, C. Y. %A Pedrero, Z. %A Gentes, S. %A Barre, J. %A Renedo, M. %A Tessier, E. %A Beraitt, S. %A Maury-Brachet, R. %A Mesmer-Dudons, N. %A Baudrimont, M. %A Legeay, A. %A Maurice, Laurence %A Gonzalez, P. %A Amouroux, D. %T Specificpathways of dietary methylmercury and inorganic mercury determined by mercury speciation and isotopic composition in zebrafish (Danio rerio) %D 2015 %L fdi:010065461 %G ENG %J Environmental Science and Technology %@ 0013-936X %M ISI:000364355300044 %N 21 %P 12984-12993 %R 10.1021/acs.est.5b03587 %U https://www.documentation.ird.fr/hor/fdi:010065461 %> https://www.documentation.ird.fr/intranet/publi/2015/12/010065461.pdf %V 49 %W Horizon (IRD) %X An original approach is proposed to investigate inorganic (iHg) and methylinercury (MeHg) trophic transfer and fate in a model fish, Danio rerio, by combining natural isotopic fractionation and speciation. Animals were exposed to three different dietary conditions: (1) 50 ng Hg g(-1), 80% as MeHg; (2) diet enriched in MeHg 10 000 ng Hg g(-1), 95% as MeHg, and (3) diet enriched in iHg 10 000 ng Hg g(-1), 99% as iHg. Harvesting was carried out after 0, 7, 25, and 62 days. Time-dependent Hg species distribution and isotopic fractionation in fish organs (muscle, brain, liver) and feces, exhibited different patterns, as a consequence of their dissimilar metabolization. The rapid isotopic re-equilibration to the new MeHg-food source reflects its high bioaccumulation rate. Relevant aspects related to Hg excretion are also described. This study confirms Hg isotopic fractionation as a powerful tool to investigate biological processes, although its deconvolution and fully understanding is still a challenge. %$ 036