@article{fdi:010065387,
  title = {{P}opulation susceptibility to a variant swine-origin influenza virus {A}({H}3{N}2) in {V}ietnam, 2011-2012},
  author = {{H}oa, {L}. {N}. {M}. and {B}ryant, {J}. {E}. and {C}hoisy, {M}arc and {N}guyet, {L}. {A}. and {B}ao, {N}. {T}. and {T}rang, {N}. {H}. and {C}huc, {N}. {T}. {K}. and {T}oan, {T}. {K}. and {S}aito, {T}. and {T}akemae, {N}. and {H}orby, {P}. and {W}ertheim, {H}. and {F}ox, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A} reassortant swine-origin {A}({H}3{N}2) virus ({A}/swine/{B}inh{D}uong/03-9/2010) was detected through swine surveillance programmes in southern {V}ietnam in 2010. {T}his virus contains haemagglutinin and neuraminidase genes from a human {A}({H}3{N}2) virus circulating around 2004-2006, and the internal genes from triple-reassortant swine influenza {A} viruses ({IAV}s). {T}o assess population susceptibility to this virus we measured haemagglutination inhibiting ({HI}) titres to {A}/swine/{B}inh{D}uong/03-9/2010 and to seasonal {A}/{P}erth/16/2009 for 947 sera collected from urban and rural {V}ietnamese people during 2011-2012. {S}eroprevalence ({HI} >= 40) was high and similar for both viruses, with 62.6% [95% confidence interval ({CI}) 59.4-65.7] against {A}/{P}erth/16/2009 and 54.6% (95% {CI} 51.4-57.8%) against {A}/swine/{B}inh{D}uong/03-9/2010, and no significant differences between urban and rural participants. {C}hildren aged <5 years lacked antibodies to the swine origin {H}3 virus despite high seroprevalence for {A}/{P}erth/16/2009. {T}hese results reveal vulnerability to infection to this contemporary swine {IAV} in children aged <5 years; however, cross-reactive immunity in adults would likely limit epidemic emergence potential.},
  keywords = {{I}nfluenza {A} ; virology (human) and epidemiology ; zoonoses ; {VIET} {NAM}},
  booktitle = {},
  journal = {{E}pidemiology and {I}nfection},
  volume = {143},
  numero = {14},
  pages = {2959--2964},
  ISSN = {0950-2688},
  year = {2015},
  DOI = {10.1017/s0950268815000187},
  URL = {https://www.documentation.ird.fr/hor/fdi:010065387},
}