@article{fdi:010065376, title = {{B}eta-{N}-methylamino-{L}-alanine ({BMAA}) and isomers : distribution in different food web compartments of {T}hau lagoon, {F}rench {M}editerranean {S}ea}, author = {{R}eveillon, {D}. and {A}badie, {E}. and {S}echet, {V}. and {M}asseret, {E}stelle and {H}ess, {P}. and {A}mzil, {Z}.}, editor = {}, language = {{ENG}}, abstract = {{T}he neurotoxin {BMAA} (beta-{N}-methylamino-{L}-alanine) and its isomer {DAB} (2,4-diaminobutyric acid) have been detected in seafood worldwide, including in {T}hau lagoon ({F}rench {M}editerranean {S}ea). {A} cluster of amyotrophic lateral sclerosis ({ALS}), a neurodegenerative disease associated with {BMAA}, has also been observed in this region. {M}ussels, periphyton (i.e. biofilms attached to mussels) and plankton were sampled between {J}uly 2013 and {O}ctober 2014, and analyzed using {HILIC}-{MS}/{MS}. {BMAA}, {DAB} and {AEG} ({N}-(2-aminoethyl)glycine) were found in almost all the samples of the lagoon. {BMAA} and {DAB} were present at 0.58 and 0.83, 2.6 and 33, 4.0 and 7.2 mu g g(-1) dry weight in plankton collected with nets, periphyton and mussels, respectively. {S}ynechococcus sp., {O}streococcus tauri, {A}lexandrium catenella and eight species of diatoms were cultured and screened for {BMAA} and analogs. {W}hile {S}ynechococcus sp., {O}. tauri and {A}. catenella did not produce {BMAA} under our culture conditions, four diatoms species contained both {BMAA} and {DAB}. {H}ence, diatoms may be a source of {BMAA} for mussels. {U}nlike other toxins produced by microalgae, {BMAA} and {DAB} were detected in significant amounts in tissues other than digestive glands in mussels.}, keywords = {{BMAA} ; {D}iatoms ; {C}haetoceros sp. ; {S}eston ; {M}ytilus galloprovincialis ; {HILIC}-{MS}/{MS} ; {FRANCE} ; {MEDITERRANEE} ; {THAU} {ETANG}}, booktitle = {}, journal = {{M}arine {E}nvironmental {R}esearch}, volume = {110}, numero = {}, pages = {8--18}, ISSN = {0141-1136}, year = {2015}, DOI = {10.1016/j.marenvres.2015.07.015}, URL = {https://www.documentation.ird.fr/hor/fdi:010065376}, }