@article{fdi:010065319,
  title = {{T}he detection of vector-borne-disease-related {DNA} in human stool paves the way to large epidemiological studies},
  author = {{K}eita, {A}. {K}. and {F}enollar, {F}. and {S}ocolovschi, {C}. and {R}atmanov, {P}. and {B}assene, {H}. and {S}okhna, {C}heikh and {T}all, {A}. and {M}ediannikov, {O}leg and {R}aoult, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he detection of {P}lasmodium spp. by the molecular analysis of human feces was reported to be comparable to detection in the blood. {W}e believe that for epidemiological studies using molecular tools, it would be simpler to use feces, which are easier to obtain and require no training for their collection. {O}ur aim was to evaluate the usefulness of feces for the detection of these pathogens towards developing a new tool for their surveillance. {B}etween 2008 and 2010, 451 human fecal samples were collected in two {S}enegalese villages in which malaria and rickettsioses are endemic. {R}ickettsia and {P}lasmodium {DNA} were detected using quantitative {PCR} targeting {R}ickettsia of the spotted fever group, {R}. felis and {P}lasmodium spp. {T}wo different sequences were systematically targeted for each pathogen. {T}wenty of the 451 fecal samples (4.4 %) were positive for {R}ickettsia spp., including 8 for {R}. felis. {I}nhabitants of {D}ielmo were more affected (18/230, 7.8 %; p = 0.0008) compared to those of {N}diop (2/221, 0.9 %). {C}hildren under 15 years of age were more often positive (19/285, 6.7 %) than were older children (1/166, 0.6 %; p = 0.005, odds ratio = 11.79). {O}nly one sample was positive for {P}lasmodium spp. {T}his prevalence is similar to that found in the blood of the {S}enegalese population reported previously. {T}his preliminary report provides a proof of concept for the use of feces for detecting human pathogens, including microorganisms that do not cause gastroenteritis, in epidemiological studies.},
  keywords = {{R}ickettsia spp. ; {P}lasmodium spp. ; {F}ecal samples ; {H}uman ; {A}frica ; {SENEGAL} ; {FRANCE}},
  booktitle = {},
  journal = {{E}uropean {J}ournal of {E}pidemiology},
  volume = {30},
  numero = {9},
  pages = {1021--1026},
  ISSN = {0393-2990},
  year = {2015},
  DOI = {10.1007/s10654-015-0022-9},
  URL = {https://www.documentation.ird.fr/hor/fdi:010065319},
}