@article{fdi:010064895, title = {{M}ycobacterium ulcerans dynamics in aquatic ecosystems are driven by a complex interplay of abiotic and biotic factors}, author = {{G}architorena, {A}ndres and {G}u{\'e}gan, {J}ean-{F}ran{\c{c}}ois and {L}{\'e}ger, {L}. and {E}yangoh, {S}. and {M}arsollier, {L}. and {R}oche, {B}enjamin}, editor = {}, language = {{ENG}}, abstract = {{H}ost-parasite interactions are often embedded within complex host communities and can be influenced by a variety of environmental factors, such as seasonal variations in climate or abiotic conditions in water and soil, which confounds our understanding of the main drivers of many multi-host pathogens. {H}ere, we take advantage of a combination of large environmental data sets on {M}ycobacterium ulcerans ({MU}), an environmentally persistent microorganism associated to freshwater ecosystems and present in a large variety of aquatic hosts, to characterize abiotic and biotic factors driving the dynamics of this pathogen in two regions of {C}ameroon. {W}e find that {MU} dynamics are largely driven by seasonal climatic factors and certain physico-chemical conditions in stagnant and slow-flowing ecosystems, with an important role of p{H} as limiting factor. {F}urthermore, water conditions can modify the effect of abundance and diversity of aquatic organisms on {MU} dynamics, which suggests a different contribution of two {MU} transmission routes for aquatic hosts (trophic vs environmental transmission) depending on local abiotic factors.}, keywords = {{CAMEROUN}}, booktitle = {}, journal = {{E}-{L}ife}, volume = {4}, numero = {}, pages = {art. e07616 [19 ]}, ISSN = {2050-084{X}}, year = {2015}, DOI = {10.7554/e{L}ife.07616}, URL = {https://www.documentation.ird.fr/hor/fdi:010064895}, }