@article{fdi:010064813, title = {{T}emperature and the field stability of a dengue rapid diagnostic test in the tropics}, author = {{P}hommasone, {K}. and {S}engvilaipaseuth, {O}. and de {L}amballerie, {X}avier and {V}ongsouvath, {M}. and {P}honemixay, {O}. and {B}lacksell, {S}. {D}. and {N}ewton, {P}. {N}. and {D}ubot {P}{\'e}r{\`e}s, {A}udrey}, editor = {}, language = {{ENG}}, abstract = {{T}he global incidence of dengue has increased significantly in recent decades, resulting in a large public health burden in tropical and subtropical countries. {D}engue rapid diagnostic tests ({RDT}s) can provide accurate, rapid accessible diagnosis for patient management and may be easily used by health workers in rural areas. {H}owever, in dengue-endemic areas, ambient temperatures are often higher than manufacturer's recommendation. {W}e therefore evaluated the effect of high temperature over time on the performance of one commonly used dengue {RDT}, the {S}tandard {D}iagnostics {B}ioline {D}engue {D}uo. {RDT}s were kept in five different conditions (at 4 degrees {C}, 35 degrees {C}, 45 degrees {C}, 60 degrees {C}, and at fluctuant ambient temperatures in a free-standing hut) for between 2 days and 2 years in the {L}ao {P}eople's {D}emocratic {R}epublic ({PDR}). {RDT}s were tested with four control sera (negative, dengue nonstructural protein 1 [{NS}1], anti-dengue immunoglobulin [{I}g] {M}, and anti-dengue {I}g{G} positive). {T}he {RDT}s had 100% consistency over the 2-year study, despite high temperatures, including in the hut in which temperatures exceeded the manufacturer's recommendations for 29% of time points. {T}hese data suggest that the diagnostic accuracy of the {SD} {B}ioline {D}engue {D}uo {RDT} remains stable even after long-term storage at high temperatures. {T}herefore, use at such ambient temperatures in tropical areas should not jeopardize the dengue diagnostic outcome.}, keywords = {{LAOS} ; {ZONE} {TROPICALE}}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {93}, numero = {1}, pages = {33--39}, ISSN = {0002-9637}, year = {2015}, DOI = {10.4269/ajtmh.15-0142}, URL = {https://www.documentation.ird.fr/hor/fdi:010064813}, }