@article{fdi:010064812,
  title = {{D}oes host receptivity or host exposure drives dynamics of infectious diseases ? {T}he case of {W}est {N}ile {V}irus in wild birds},
  author = {{R}oche, {B}enjamin and {M}orand, {S}. and {E}lguero, {E}ric and {B}alenghien, {T}. and {G}u{\'e}gan, {J}ean-{F}ran{\c{c}}ois and {G}aidet, {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}nfection is a complex biological process involving reciprocally both the intensity of host exposure to a pathogen as well as the host intrinsic "receptivity", or permissiveness to infection. {D}isentangling their respective contributions is currently seen as a fundamental gap in our knowledge. {H}ere, we take the advantage of a rare semi-natural experiment context provided by the emergence of the {W}est {N}ile {V}irus ({WNV}) in {N}orth {A}merica. {F}ocusing on the pathogen emergence period, we combine datasets from (i) wild birds exposed to {WNV} in an urban zoo to evaluate the species intrinsic receptivity to {WNV} infection in an environment where exposure to {WNV} vectors can be assumed to be relatively homogenous for all captive species, and (ii) from free-ranging birds in their natural habitat where species ecological traits is expected to influence their exposure to {WNV} vectors. {W}e show that ecological trait and intrinsic receptivity to infection both contribute similarly to the species variation in {WNV} seroprevalence, but considering only one of them can lead to erroneous conclusions. {W}e then argue that degree of pathogen host specialization could be a fundamental factor for the respective contribution of species exposure and receptivity for numerous pathogens.},
  keywords = {{M}ulti-host pathogen ; {I}nfection process ; {W}est {N}ile ; {R}eceptivity ; {E}cological factors ; {ETATS} {UNIS}},
  booktitle = {},
  journal = {{I}nfection {G}enetics and {E}volution},
  volume = {33},
  numero = {},
  pages = {11--19},
  ISSN = {1567-1348},
  year = {2015},
  DOI = {10.1016/j.meegid.2015.04.011},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064812},
}