@article{fdi:010064804,
  title = {{R}isk factors associated with ebola and marburg viruses seroprevalence in blood donors in the {R}epublic of {C}ongo},
  author = {{M}oyen, {N}. and {T}hirion, {L}aurence and {E}mmerich, {P}. and {D}zia-{L}epfoundzou, {A}. and {R}ichet, {H}. and {B}oehmann, {Y}. and {D}imi, {Y}. and {G}allian, {P}. and {G}ould, {E}. {A}. and {G}unther, {S}. and de {L}amballerie, {X}avier},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {E}bola and {M}arburg viruses (family {F}iloviridae, genera {E}bolavirus and {M}arburgvirus) cause haemorrhagic fevers in humans, often associated with high mortality rates. {T}he presence of antibodies to {E}bola virus ({EBOV}) and {M}arburg virus ({MARV}) has been reported in some {A}frican countries in individuals without a history of haemorrhagic fever. {I}n this study, we present a {MARV} and {EBOV} seroprevalence study conducted amongst blood donors in the {R}epublic of {C}ongo and the analysis of risk factors for contact with {EBOV}. {M}ethodology and {F}indings {I}n 2011, we conducted a {MARV} and {EBOV} seroprevalence study amongst 809 blood donors recruited in rural (75; 9.3%) and urban (734; 90.7%) areas of the {R}epublic of {C}ongo. {S}erum titres of {I}g{G} antibodies to {MARV} and {EBOV} were assessed by indirect double-immunofluorescence microscopy. {MARV} seroprevalence was 0.5% (4 in 809) without any identified risk factors. {P}revalence of {I}g{G} to {EBOV} was 2.5%, peaking at 4% in rural areas and in {P}ointe {N}oire. {I}ndependent risk factors identified by multivariate analysis were contact with bats and exposure to birds. {C}onclusions/{S}ignificance {T}his {MARV} and {EBOV} serological survey performed in the {R}epublic of {C}ongo identifies a probable role for environmental determinants of exposure to {EBOV}. {I}t highlights the requirement for extending our understanding of the ecological and epidemiological risk of bats (previously identified as a potential ecological reservoir) and birds as vectors of {EBOV} to humans, and characterising the protection potentially afforded by {EBOV}-specific antibodies as detected in blood donors.},
  keywords = {{CONGO}},
  booktitle = {},
  journal = {{P}los {N}eglected {T}ropical {D}iseases},
  volume = {9},
  numero = {6},
  pages = {e0003833 [15 p.]},
  ISSN = {1935-2735},
  year = {2015},
  DOI = {10.1371/journal.pntd.0003833},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064804},
}