De Meeûs Thierry. (2015). Genetic identities and local inbreeding in pure diploid clones with homoplasic markers : SNPs may be misleading [plus Corrigendum, 2016, vol. 42, p. 83]. Infection Genetics and Evolution, 33, p. 227-232. ISSN 1567-1348.
Titre du document
Genetic identities and local inbreeding in pure diploid clones with homoplasic markers : SNPs may be misleading [plus Corrigendum, 2016, vol. 42, p. 83]
Infection Genetics and Evolution, 2015,
33, p. 227-232 ISSN 1567-1348
Expected values for observed heterozygosity, genetic diversity, and inbreeding of individuals relative to inbreeding of the population (F-IS) are derived in the case of one locus displaying homoplasy with K possible allelic states (RAM model) in a clonal diploid population. Heterozygosity (H-O) and genetic diversity (H-S) are substantially affected by homoplasy as long as the number of alleles K <= 10, while F-IS remains weakly affected in any case. Simulations suggest that in big populations, or in case of maximum homoplasy (K = 2), expected values can appear far from the observed ones because equilibrium takes too many generations to be reached at homoplasic markers in clonally propagating populations. This raises some concern on the use of SNPs, at least in clonal populations.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020]
