@article{fdi:010064776, title = {{A}ssessment of the {E}uropean flounder responses to chemical stress in the {E}nglish {C}hannel, considering biomarkers and life history traits}, author = {{D}upuy, {C}. and {G}alland, {C}. and {P}ichereau, {V}. and {S}anchez, {W}. and {R}iso, {R}. and {L}abonne, {M}aylis and {A}mara, {R}. and {C}harrier, {G}. and {F}ournier, {M}. and {L}aroche, {J}.}, editor = {}, language = {{ENG}}, abstract = {{A} multi-biomarker approach was developed to evaluate responses of {E}uropean flounder ({P}latichthys flesus) in three contrasted estuaries over the {E}nglish {C}hannel: the {C}anche (pristine site), {T}amar (heavy metals and {PAH}s contamination) and {S}eine (heavily pollution with a complex cocktail of contaminants). {T}he condition factor and several biomarkers of the immune system, antioxidant enzymes, energetic metabolism and detoxification processes were investigated in young-of-the-year (0+) and one-year-old (1+) flounder. {R}esults underlined the difference between the pristine site and the {S}eine estuary which showed a lower condition factor, a modulation of the immune system, a higher {C}ytochrome {C} oxidase activity, and an up-regulation of {BHMT} expression. {T}he moderate biomarker responses in the {T}amar fish could be linked to the specific contamination context of this estuary. {F}lounder life history traits were analyzed by otolith microchemistry, in order to depict how the fish use their habitat and thus respond to chemical stress in estuaries.}, keywords = {{P}ollution ; {E}stuaries ; {F}ish ; {I}mmunotoxicity ; {G}ene expression ; {L}ife-history traits ; {MANCHE}}, booktitle = {}, journal = {{M}arine {P}ollution {B}ulletin}, volume = {95}, numero = {2}, pages = {634--645}, ISSN = {0025-326{X}}, year = {2015}, DOI = {10.1016/j.marpolbul.2014.11.033}, URL = {https://www.documentation.ird.fr/hor/fdi:010064776}, }