@article{fdi:010064744, title = {{A}dult blood-feeding tsetse flies, trypanosomes, microbiota and the fluctuating environment in sub-{S}aharan {A}frica}, author = {{G}eiger, {A}nne and {P}onton, {F}. and {S}imo, {G}.}, editor = {}, language = {{ENG}}, abstract = {{T}he tsetse fly vector transmits the protozoan {T}rypanosoma brucei, responsible for {H}uman {A}frican {T}rypanosomiasis, one of the most neglected tropical diseases. {D}espite a recent decline in new cases, it is still crucial to develop alternative strategies to combat this disease. {H}ere, we review the literature on the factors that influence trypanosome transmission from the fly vector to its vertebrate host (particularly humans). {T}hese factors include climate change effects to pathogen and vector development (in particular climate warming), as well as the distribution of host reservoirs. {F}inally, we present reports on the relationships between insect vector nutrition, immune function, microbiota and infection, to demonstrate how continuing research on the evolving ecology of these complex systems will help improve control strategies. {I}n the future, such studies will be of increasing importance to understand how vector-borne diseases are spread in a changing world.}, keywords = {{AFRIQUE} {SUBSAHARIENNE}}, booktitle = {}, journal = {{I}sme {J}ournal}, volume = {9}, numero = {7}, pages = {1496--1507}, ISSN = {1751-7362}, year = {2015}, DOI = {10.1038/ismej.2014.236}, URL = {https://www.documentation.ird.fr/hor/fdi:010064744}, }