@article{fdi:010064700,
  title = {{M}alaria in pregnancy is a predictor of infant haemoglobin concentrations during the first year of life in {B}enin, {W}est {A}frica},
  author = {{A}ccrombessi, {M}. and {O}uedraogo, {S}. and {A}gbota, {G}. {C}. and {G}onzalez, {R}. and {M}assougbodji, {A}. and {M}enendez, {C}. and {C}ot, {M}ichel},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {A}naemia is an increasingly recognized health problem in {A}frica, particularly in infants and pregnant women. {A}lthough malaria is known to be the main risk factor of anaemia in both groups, the consequences of maternal factors, particularly malaria in pregnancy ({M}i{P}), on infant haemoglobin ({H}b) concentrations during the first months of life are still unclear. {M}ethods {W}e followed-up a cohort of 1005 {B}eninese pregnant women from the beginning of pregnancy until delivery. {A} subsample composed of the first 400 offspring of these women were selected at birth and followed until the first year of life. {P}lacental histology and blood smear at 1st clinical antenatal visit ({ANC}), 2nd {ANC} and delivery were used to assess malaria during pregnancy. {I}nfant {H}b concentrations were measured at birth, 6, 9 and 12 months of age. {A} mixed multi-level model was used to assess the association between {M}i{P} and infant {H}b variations during the first 12 months of life. {R}esults {P}lacental malaria (difference mean [dm] = -2.8 g/{L}, 95% {CI} [-5.3, -0.3], {P} = 0.03) and maternal peripheral parasitaemia at delivery (dm = -4.6 g/{L}, 95% {CI} [-7.9, -1.3], {P} = 0.007) were the main maternal factors significantly associated with infant {H}b concentrations during the first year of life. {P}oor maternal nutritional status and malaria infection during infancy were also significantly associated with a decrease in infant {H}b. {C}onclusion {A}ntimalarial control and nutritional interventions before and during pregnancy should be reinforced to reduce specifically the incidence of infant anaemia, particularly in {S}ub{S}aharan countries.},
  keywords = {{BENIN}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {10},
  numero = {6},
  pages = {e0129510 [17 p.]},
  ISSN = {1932-6203},
  year = {2015},
  DOI = {10.1371/journal.pone.0129510},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064700},
}