@article{fdi:010064213,
  title = {{H}igh plasma levels of soluble endothelial protein {C} receptor are associated with increased mortality among children with cerebral malaria in {B}enin},
  author = {{M}oussiliou, {A}. and {A}lao, {M}. {J}. and {D}enoeud {N}dam, {L}ise and {T}ahar, {R}achida and {E}zimegnon, {S}. and {S}agbo, {G}. and {A}moussou, {A}. and {L}uty, {A}drian and {D}eloron, {P}hilippe and {T}uikue {N}dam, {N}icaise},
  editor = {},
  language = {{ENG}},
  abstract = {{L}oss of endothelial protein {C} receptor ({EPCR}) occurs at the sites of {P}lasmodium falciparum-infected erythrocyte sequestration in patients with or who died from cerebral malaria. {I}n children presenting with different clinical syndromes of malaria, we assessed the relationships between endogenous plasma soluble {EPCR} (s{EPCR}) levels and clinical presentation or mortality. {A}fter adjustment for age, for treatment before admission, and for a known genetic factor, s{EPCR} level at admission was positively associated with cerebral malaria ({P} = .011) and with malaria-related mortality ({P} = .0003). {M}easuring s{EPCR} levels at admission could provide an early biological marker of the outcome of cerebral malaria.},
  keywords = {plasmodium ; cerebral malaria ; {EPCR} ; s{EPCR} ; protein {C} ; {BENIN}},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {211},
  numero = {9},
  pages = {1484--1488},
  ISSN = {0022-1899},
  year = {2015},
  DOI = {10.1093/infdis/jiu661},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064213},
}