@article{fdi:010064179, title = {{M}ultilocus microsatellite typing of {L}eishmania and clinical applications : a review}, author = {{A}luru, {S}. and {H}ide, {M}. and {M}ichel, {G}. and {B}anuls, {A}nne-{L}aure and {M}arty, {P}. and {P}omares, {C}.}, editor = {}, language = {{ENG}}, abstract = {{M}icrosatellite markers have been used for {L}eishmania genetic studies worldwide, giving useful insight into leishmaniasis epidemiology. {U}nderstanding the geographic distribution, dynamics of {L}eishmania populations, and disease epidemiology improved markedly with this tool. {I}n endemic foci, the origins of antimony-resistant strains and multidrug treatment failures were explored with multilocus microsatellite typing ({MLMT}). {H}igh genetic variability was detected but no association between parasite genotypes and drug resistance was established. {A}n association between {MLMT} profiles and clinical disease manifestations was highlighted in only three studies and this data needs further confirmation. {A}t the individual level, {MLMT} provided information on relapse and reinfection when multiple leishmaniasis episodes occurred. {T}his information could improve knowledge of epidemiology and guide therapeutic choices for active chronic visceral leishmaniasis, the disease form in some {HIV}-positive patients.}, keywords = {{L}eishmania ; {M}icrosatellite ; {G}enotyping ; {M}olecular epidemiology ; {M}ultilocus microsatellite typing ({MLMT})}, booktitle = {}, journal = {{P}arasite}, volume = {22}, numero = {}, pages = {art. 16 [8 ]}, ISSN = {1252-607{X}}, year = {2015}, DOI = {10.1051/parasite/2015016}, URL = {https://www.documentation.ird.fr/hor/fdi:010064179}, }