@article{fdi:010064135,
  title = {{I}mpact of helminth infection during pregnancy on cognitive and motor functions of one-year-old children},
  author = {{M}ireku, {M}. {O}. and {B}oivin, {M}. {J}. and {D}avidson, {L}. {L}. and {O}uedraogo, {S}. and {K}oura, {G}. {K}. and {A}lao, {M}. {J}. and {M}assougbodji, {A}. and {C}ot, {M}ichel and {B}odeau-{L}ivinec, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{O}bjective {T}o determine the effect of helminth infection during pregnancy on the cognitive and motor functions of one-year-old children. {M}ethods {S}ix hundred and thirty five singletons born to pregnant women enrolled before 29 weeks of gestation in a trial comparing two intermittent preventive treatments for malaria were assessed for cognitive andmotor functions using the {M}ullen {S}cales of {E}arly {L}earning, in the {TOVI} study, at twelve months of age in the district of {A}llada in {B}enin. {S}tool samples of pregnant women were collected at recruitment, second antenatal care ({ANC}) visit (at least one month after recruitment) and just before delivery, and were tested for helminths using the {K}ato-{K}atz technique. {A}ll pregnant women were administered a total of 600 mg ofmebendazole (100 mg two times daily for 3 days) to be taken after the first {ANC} visit. {T}he intake was not directly observed. {R}esults {P}revalence of helminth infection was 11.5%, 7.5% and 3.0% at first {ANC} visit, second {ANC} visit and at delivery, respectively. {C}hildren of mothers who were infected with hookworms at the first {ANC} visit had 4.9 (95% {CI}: 1.3-8.6) lower mean gross motor scores compared to those whose mothers were not infected with hookworms at the first {ANC} visit, in the adjusted model. {H}elminth infection at least once during pregnancy was associated with infant cognitive and gross motor functions after adjusting for maternal education, gravidity, child sex, family possessions, and quality of the home stimulation. {C}onclusion {H}elminth infection during pregnancy is associated with poor cognitive and gross motor outcomes in infants. {M}easures to prevent helminth infection during pregnancy should be reinforced.},
  keywords = {{BENIN}},
  booktitle = {},
  journal = {{P}los {N}eglected {T}ropical {D}iseases},
  volume = {9},
  numero = {3},
  pages = {e0003463 [16 p.]},
  ISSN = {1935-2735},
  year = {2015},
  DOI = {10.1371/journal.pntd.0003463},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064135},
}