@article{fdi:010064064,
  title = {{E}volution of dengue disease and entomological monitoring in {S}anta {C}ruz, {B}olivia 2002-2008},
  author = {{B}r{\'e}mond, {P}hilippe and {R}oca, {Y}. and {B}reni{\`e}re, {S}imone {F}r{\'e}d{\'e}rique and {W}alter, {A}nnie and {B}arja-{S}imon, {Z}. and {F}ernandez, {R}. {T}. and {V}argas, {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {I}n the context of a rapid increase of dengue cases in the {A}mericas, a monitoring system based on systematic serological control ({I}g{M}) of patients consulting for suspected dengue was developed in {B}olivia at the end of the 1990s. {I}n the most affected city of {S}anta {C}ruz, this system was complemented by an entomological surveillance program based on periodical search for immature stages of {A}edes aegypti in dwelling water-holding containers. {H}ere, we analyze these data and describe dengue patterns over 6 years (2002-2008), highlighting the spatial distribution of patients and vectors. {M}ethodology/{P}rincipal {F}indings {D}ata mining concerned six annual epidemic cycles (2002-2008), with continuous serological and clinical results and entomological data from 16 surveys, examined at the scales of 36 urban areas and four concentric areas covering the entire city. {A}nnual incidence varied from 0.28% to 0.95%; overall incidence was higher in women and adults, and dengue dynamics followed successive periods of high ({J}anuary-{J}une) and low ({J}uly-{D}ecember) transmission. {L}ower numbers of cases from the city center to the periphery were observed, poorly related to the more homogeneous and permanent distribution of {A}. aegypti. "{P}lant pots" were a major vector source in the city center, and "{T}ires" and "{O}dds and ends" beyond the second ring of the city. {C}onclusions/{S}ignificance {O}ver the years, the increasing trend of dengue cases has been highlighted as well as its widespread distribution over the entire city, but an underestimation of the number of cases is strongly suspected. {C}ontrary to popular belief, the city center appears more affected than the periphery, and dengue is not particularly related to waste. {I}nterestingly, the clinical diagnosis of dengue by physicians improved over the years, whatever the gender, age and residential area of suspected cases.},
  keywords = {{BOLIVIE} ; {ZONE} {TROPICALE}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {10},
  numero = {2},
  pages = {e0118337 [20 p.]},
  ISSN = {1932-6203},
  year = {2015},
  DOI = {10.1371/journal.pone.0118337},
  URL = {https://www.documentation.ird.fr/hor/fdi:010064064},
}