@article{fdi:010064056, title = {{N}on-invasive tools for the diagnosis of potentially life-threatening gynaecological emergencies : a systematic review}, author = {{P}olena, {V}. and {H}uchon, {C}. and {R}amos, {C}. {V}. and {R}ouzier, {R}. and {D}umont, {A}lexandre and {F}auconnier, {A}.}, editor = {}, language = {{ENG}}, abstract = {{O}bjective {T}o identify non- invasive tools for diagnosis of the major potentially life-threatening gynaecological emergencies ({G}-{PLE}s) reported in previous studies, and to assess their diagnostic accuracy. {M}ethods {MEDLINE}; {EMBASE}; {C}ochrane {C}entral {R}egister of {C}ontrolled {T}rials ({CENTRAL}; {T}he {C}ochrane {L}ibrary) were searched to identify all eligible studies published in {E}nglish or {F}rench between {J}anuary 1990 and {D}ecember 2012. {S}tudies were considered eligible if they were primary diagnostic studies of any designs, with a gold standard and with sufficient information for construction of a 2 x 2 contingency table, concerning at least one of the following {G}-{PLE}s: complicated ectopic pregnancy, complicated pelvic inflammatory disease, adnexal torsion and haemoperitoneum of any gynaecological origin. {E}xtraction of data and assessment of study quality were conducted by two independent reviewers. {W}e set the thresholds for the diagnostic value of signs retrieved at {S}ensibility >= 95% and {LR}- <= 0.25, or {S}pecificity >= 90% and {LR}+ >= 4. {R}esults {W}e identified 8288 reports of diagnostic studies for the selected {G}-{PLE}s, 45 of which met the inclusion criteria. {T}he methodological quality of the included studies was generally low. {T}he most common diagnostic tools evaluated were transvaginal ultrasound (20/45), followed by medical history (18/45), clinical examination (15/45) and laboratory tests (14/45). {S}tandardised questioning about symptoms, systolic blood pressure < 110 mm{H}g, shock index>0.85, identification of a mass by abdominal palpation or vaginal examination, haemoglobin concentration < 10 g/dl and six ultrasound and {D}oppler signs presented high performances for the diagnosis of {G}-{PLE}s. {T}ransvaginal ultrasound was the diagnostic tool with the best individual performance for the diagnosis of all {G}-{PLE}s. {C}onclusion {T}his systematic review suggests that blood pressure measurement, haemoglobin tests and transvaginal ultrasound are cornerstone examinations for the diagnosis of {G}-{PLE}s that should be available in all gynaecological emergency care services. {S}tandardised questioning about symptoms could be used for triage of patients.}, keywords = {}, booktitle = {}, journal = {{P}los {O}ne}, volume = {10}, numero = {2}, pages = {e0114189 [17 p.]}, ISSN = {1932-6203}, year = {2015}, DOI = {10.1371/journal.pone.0114189}, URL = {https://www.documentation.ird.fr/hor/fdi:010064056}, }