@article{fdi:010064005, title = {{H}igh prevalence of {T}ropheryma whipplei in {L}ao kindergarten children}, author = {{K}eita, {A}. {K}. and {D}ubot {P}{\'e}r{\`e}s, {A}udrey and {P}hommasone, {K}. and {S}ibounheuang, {B}. and {V}ongsouvath, {M}. and {M}ayxay, {M}. and {R}aoult, {D}idier and {N}ewton, {P}. {N}. and {F}enollar, {F}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground {T}ropheryma whipplei is a bacterium commonly found in feces of young children in {A}frica, but with no data from {A}sia. {W}e estimated the prevalence of {T}. whipplei carriage in feces of children in {L}ao {PDR} ({L}aos). {M}ethods/{P}rincipal {F}indings {U}sing specific quantitative real-time {PCR}, followed by genotyping for each positive specimen, we estimated the prevalence of {T}. whipplei in 113 feces from 106 children in {V}ientiane, the {L}ao {PDR} ({L}aos). {T}. whipplei was detected in 48% (51/106) of children. {T}hose aged <= 4 years were significantly less frequently positive (17/52, 33%) than older children (34/54, 63%; p< 0.001). {P}ositive samples were genotyped. {E}ight genotypes were detected including 7 specific to {L}aos. {G}enotype 2, previously detected in {E}urope, was circulating (21% of positive children) in 2 kindergartens ({C}hompet and {A}kad). {G}enotypes 136 and 138 were specific to {C}hompet (21% and 15.8%, respectively) whereas genotype 139 was specific to {A}kad (10.55%). {C}onclusions/{S}ignificance {T}. whipplei is a widely distributed bacterium, highly prevalent in feces of healthy children in {L}aos. {F}urther research is needed to identify the public health significance of this finding.}, keywords = {{LAOS}}, booktitle = {}, journal = {{P}los {N}eglected {T}ropical {D}iseases}, volume = {9}, numero = {2}, pages = {e0003538 [10 p.]}, ISSN = {1935-2735}, year = {2015}, DOI = {10.1371/journal.pntd.0003538}, URL = {https://www.documentation.ird.fr/hor/fdi:010064005}, }