@article{fdi:010064002, title = {{T}he ongoing revolution of {MALDI}-{TOF} mass spectrometry for microbiology reaches tropical {A}frica}, author = {{F}all, {B}. and {L}o, {C}. {I}. and {S}amb-{B}a, {B}. and {P}errot, {N}. and {D}iawara, {S}. and {G}ueye, {M}. {W}. and {S}ow, {K}. and {A}ubadie-{L}adrix, {M}. and {M}ediannikov, {O}leg and {S}okhna, {C}heikh and {D}ieme, {Y}. and {C}hatellier, {S}. and {W}ade, {B}. and {R}aoult, {D}idier and {F}enollar, {F}.}, editor = {}, language = {{ENG}}, abstract = {{M}atrix-assisted laser desorption ionization time-of-flight ({MALDI}-{TOF}) mass spectrometry ({MS}) represents a revolution in routine pathogen identification in clinical microbiology laboratories. {A} {MALDI}-{TOF} {MS} was introduced to tropical {A}frica in the clinical microbiology laboratory of the {H}opital {P}rincipal de {D}akar ({S}enegal) and used for routine pathogen identification. {U}sing {MS}, 2,429 bacteria and fungi isolated from patients were directly assayed, leading to the identification of 2,082 bacteria (85.7%) and 206 fungi (8.5%) at the species level, 109 bacteria (4.5%) at the genus level, and 16 bacteria (0.75%) at the family level. {S}ixteen isolates remained unidentified (0.75%). {E}scherichia coli was the most prevalent species (25.8%) followed by {K}lebsiella pneumoniae (14.8%), {S}treptococcus agalactiae (6.2%), {A}cinetobacter baumannii (6.1%), {P}seudomonas aeruginosa (5.9%), and {S}taphylococcus aureus (5.9%). {MALDI}-{TOF} {MS} has also enabled the detection of rare bacteria and fungi. {MALDI}-{TOF} {MS} is a powerful tool for the identification of bacterial and fungal species involved in infectious diseases in tropical {A}frica.}, keywords = {{AFRIQUE} ; {ZONE} {TROPICALE} ; {SENEGAL}}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {92}, numero = {3}, pages = {641--647}, ISSN = {0002-9637}, year = {2015}, DOI = {10.4269/ajtmh.14-0406}, URL = {https://www.documentation.ird.fr/hor/fdi:010064002}, }