%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Huynh, B. T. %A Cottrell, Gilles %A Cot, Michel %A Briand, Valérie %T Burden of malaria in early pregnancy : a neglected problem ? %D 2015 %L fdi:010063971 %G ENG %J Clinical Infectious Diseases %@ 1058-4838 %K malaria ; prevention ; pregnancy complication ; time factors ; Africa %K AFRIQUE SUBSAHARIENNE ; BURKINA FASO ; CONGO ; OUGANDA ; BENIN ; MALAWI ; REPUBIQUE DEMOCRATIQUE DU CONGO %M ISI:000349764400015 %N 4 %P 598-604 %R 10.1093/cid/ciu848 %U https://www.documentation.ird.fr/hor/fdi:010063971 %> https://www.documentation.ird.fr/intranet/publi/2015/04/010063971.pdf %V 60 %W Horizon (IRD) %X According to the current World Health Organization guidelines, the drug prevention of malaria during pregnancy does not adequately cover the first trimester of gestation in high-transmission areas. Although the pathophysiological mechanisms of early infections are not completely understood yet, a review of the most recent studies on the topic suggests that their consequences are serious in terms of maternal anemia and low birth weight. Consequently, there is a need to focus on the awareness of women in a period hard to access, to develop safe drugs to be used in the first trimester, and to consider preconceptional interventions in teenage girls, such as a new malaria vaccine to be used in pregnancy. %$ 052 ; 056 ; 010