Publications des scientifiques de l'IRD

Rougeron V., De Meeûs Thierry, Banuls Anne-Laure. (2015). A primer for Leishmania population genetic studies. Trends in Parasitology, 31 (2), p. 52-59. ISSN 1471-4922.

Titre du document
A primer for Leishmania population genetic studies
Année de publication
2015
Type de document
Article référencé dans le Web of Science WOS:000349725000006
Auteurs
Rougeron V., De Meeûs Thierry, Banuls Anne-Laure
Source
Trends in Parasitology, 2015, 31 (2), p. 52-59 ISSN 1471-4922
Leishmaniases remain a major public health problem. Despite the development of elaborate experimental techniques and sophisticated statistical tools, how these parasites evolve, adapt themselves to new environmental compartments and hosts, and develop resistance to new drugs remains unclear. Leishmania parasites constitute a complex model from a biological, ecological, and epidemiological point of view but also with respect to their genetics and phylogenetics. With this in view, we seek to outline the criteria, caveats, and confounding factors to be considered for Leishmania population genetic studies. We examine how the taxonomic complexity, heterozygosity, intraspecific and interspecific recombination, aneuploidy, and ameiotic recombination of Leishmania intersect with population genetic studies of this parasite.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Entomologie médicale / Parasitologie / Virologie [052] ; Sciences du monde animal [080]
Localisation
Fonds IRD [F B010063960]
Identifiant IRD
fdi:010063960
Contact