@article{fdi:010063888,
  title = {{S}tability of the gorilla microbiome despite simian immunodeficiency virus infection},
  author = {{M}oeller, {A}. {H}. and {P}eeters, {M}artine and {A}youba, {A}hidjo and {N}gole, {E}. {M}. and {E}steban, {A}. and {H}ahn, {B}. {H}. and {O}chman, {H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{S}imian immunodeficiency viruses ({SIV}s) have been discovered in over 45 primate species; however, the pathogenic potential of most {SIV} strains remains unknown due to difficulties inherent in observing wild populations. {B}ecause those {SIV} infections that are pathogenic have been shown to induce changes in the host's gut microbiome, monitoring the microbiota present in faecal samples can provide a noninvasive means for studying the effects of {SIV} infection on the health of wild-living primates. {H}ere, we examine the effects of {SIV}gor, a close relative of {SIV}cpz of chimpanzees and {HIV}-1 of humans, on the gut bacterial communities residing within wild gorillas, revealing that gorilla gut microbiomes are exceptionally robust to {SIV} infection. {I}n contrast to the microbiomes of {HIV}-1-infected humans and {SIV}cpz-infected chimpanzees, {SIV}gor-infected gorilla microbiomes exhibit neither rises in the frequencies of opportunistic pathogens nor elevated rates of microbial turnover within individual hosts. {R}egardless of {SIV} infection status, gorilla microbiomes assort into enterotypes, one of which is compositionally analogous to those identified in humans and chimpanzees. {T}he other gorilla enterotype appears specialized for a leaf-based diet and is enriched in environmentally derived bacterial genera. {W}e hypothesize that the acquisition of this gorilla-specific enterotype was enabled by lowered immune system control over the composition of the microbiome. {O}ur results indicate differences between the pathology of {SIV}gor and {SIV}cpz/{HIV}-1 infections, demonstrating the utility of investigating host microbial ecology as a means for studying disease in wild primates of high conservation priority.},
  keywords = {bacteria ; coevolution ; community ecology ; conservation biology ; metabarcoding ; microbial biology ; {CAMEROUN}},
  booktitle = {},
  journal = {{M}olecular {E}cology},
  volume = {24},
  numero = {3},
  pages = {690--697},
  ISSN = {0962-1083},
  year = {2015},
  DOI = {10.1111/mec.13057},
  URL = {https://www.documentation.ird.fr/hor/fdi:010063888},
}