N'Dilimabaka N., Berthet N., Rougeron V., Mangombi J. B., Durand P., Maganga G. D., Bouchier C., Schneider B. S., Fair J., Renaud F., Leroy Eric. (2015). Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in domestic mice in Gabon : risk of emergence of LCMV encephalitis in Central Africa. Journal of Virology, 89 (2), p. 1456-1460. ISSN 0022-538X.
Titre du document
Evidence of Lymphocytic Choriomeningitis Virus (LCMV) in domestic mice in Gabon : risk of emergence of LCMV encephalitis in Central Africa
N'Dilimabaka N., Berthet N., Rougeron V., Mangombi J. B., Durand P., Maganga G. D., Bouchier C., Schneider B. S., Fair J., Renaud F., Leroy Eric
Source
Journal of Virology, 2015,
89 (2), p. 1456-1460 ISSN 0022-538X
Lymphocytic choriomeningitis virus (LCMV) can cause acute fatal disease on all continents but was never detected in Africa. We report the first detection of LCMV RNA in a common European house mouse (Mus musculus domesticus) in Africa. Phylogenetic analyses show a close relationship with North American strains. These findings suggest that there is a risk of the appearance of LCMV acute encephalitis cases. This is a perfect example of virus dissemination by its natural host that may have dramatic public health consequences.
