@article{fdi:010063106,
  title = {{E}bola virus disease in the {D}emocratic {R}epublic of {C}ongo},
  author = {{M}aganga, {G}. {D}. and {K}apetshi, {J}. and {B}erthet, {N}. and {I}lunga, {B}. {K}. and {K}abange, {F}. and {K}ingebeni, {P}. {M}. and {M}ondonge, {V}. and {M}uyembe, {J}. {J}. {T}. and {B}ertherat, {E}. and {B}riand, {S}. and {C}abore, {J}. and {E}pelboin, {A}. and {F}ormenty, {P}. and {K}obinger, {G}. and {G}onzalez-{A}ngulo, {L}. and {L}abouba, {I}. and {M}anuguerra, {J}. {C}. and {O}kwo-{B}ele, {J}. {M}. and {D}ye, {C}. and {L}eroy, {E}ric},
  editor = {},
  language = {{ENG}},
  abstract = {{BACKGROUND} {T}he seventh reported outbreak of {E}bola virus disease ({EVD}) in the equatorial {A}frican country of the {D}emocratic {R}epublic of {C}ongo ({DRC}) began on {J}uly 26, 2014, as another large {EVD} epidemic continued to spread in {W}est {A}frica. {S}imultaneous reports of {EVD} in equatorial and {W}est {A}frica raised the question of whether the two outbreaks were linked. {METHODS} {W}e obtained data from patients in the {DRC}, using the standard {W}orld {H}ealth {O}rganization clinical-investigation form for viral hemorrhagic fevers. {P}atients were classified as having suspected, probable, or confirmed {EVD} or a non-{EVD} illness. {B}lood samples were obtained for polymerase-chain-reaction-based diagnosis, viral isolation, sequencing, and phylogenetic analysis. {RESULTS} {T}he outbreak began in {I}nkanamongo village in the vicinity of {B}oende town in {E}quateur province and has been confined to that province. {A} total of 69 suspected, probable, or confirmed cases were reported between {J}uly 26 and {O}ctober 7, 2014, including 8 cases among health care workers, with 49 deaths. {A}s of {O}ctober 7, there have been approximately six generations of cases of {EVD} since the outbreak began. {T}he reported weekly case incidence peaked in the weeks of {A}ugust 17 and 24 and has since fallen sharply. {G}enome sequencing revealed {E}bola virus ({EBOV}, {Z}aire species) as the cause of this outbreak. {A} coding-complete genome sequence of {EBOV} that was isolated during this outbreak showed 99.2% identity with the most closely related variant from the 1995 outbreak in {K}ikwit in the {DRC} and 96.8% identity to {EBOV} variants that are currently circulating in {W}est {A}frica. {CONCLUSIONS} {T}he current {EVD} outbreak in the {DRC} has clinical and epidemiologic characteristics that are similar to those of previous {EVD} outbreaks in equatorial {A}frica. {T}he causal agent is a local {EBOV} variant, and this outbreak has a zoonotic origin different from that in the 2014 epidemic in {W}est {A}frica.},
  keywords = {{REPUBLIQUE} {DEMOCRATIQUE} {DU} {CONGO}},
  booktitle = {},
  journal = {{N}ew {E}ngland {J}ournal of {M}edicine},
  volume = {371},
  numero = {22},
  pages = {2083--2091},
  ISSN = {0028-4793},
  year = {2014},
  DOI = {10.1056/{NEJM}oa1411099},
  URL = {https://www.documentation.ird.fr/hor/fdi:010063106},
}