Moeller A. H., Li Y. Y., Ngole E. M., Ahuka-Mundeke S., Lonsdorf E. V., Pusey A. E., Peeters Martine, Hahn B. H., Ochman H. (2014). Rapid changes in the gut microbiome during human evolution. Proceedings of the National Academy of Sciences of the United States of America, 111 (46), p. 16431-16435. ISSN 0027-8424.
Titre du document
Rapid changes in the gut microbiome during human evolution
Moeller A. H., Li Y. Y., Ngole E. M., Ahuka-Mundeke S., Lonsdorf E. V., Pusey A. E., Peeters Martine, Hahn B. H., Ochman H.
Source
Proceedings of the National Academy of Sciences of the United States of America, 2014,
111 (46), p. 16431-16435 ISSN 0027-8424
Humans are ecosystems containing trillions of microorganisms, but the evolutionary history of this microbiome is obscured by a lack of knowledge about microbiomes of African apes. We sequenced the gut communities of hundreds of chimpanzees, bonobos, and gorillas and developed a phylogenetic approach to reconstruct how present-day human microbiomes have diverged from those of ancestral populations. Compositional change in the microbiome was slow and clock-like during African ape diversification, but human microbiomes have deviated from the ancestral state at an accelerated rate. Relative to the microbiomes of wild apes, human microbiomes have lost ancestral microbial diversity while becoming specialized for animal-based diets. Individual wild apes cultivate more phyla, classes, orders, families, genera, and species of bacteria than do individual humans across a range of societies. These results indicate that humanity has experienced a depletion of the gut flora since diverging from Pan.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020]
;
Santé : généralités [050]
;
Nutrition, alimentation [054]
;
Sciences du monde animal [080]
