@article{fdi:010062711,
  title = {{M}ycobacterium bovis in {B}urkina {F}aso : epidemiologic and genetic links between human and cattle isolates},
  author = {{S}anou, {A}dama and {T}arnagda, {Z}. and {K}anyala, {E}. and {Z}ingue, {D}. and {N}ouctara, {M}. and {G}aname, {Z}. and {C}ombary, {A}. and {H}ien, {H}. and {D}embele, {M}. and {K}abor{\'e}, {A}. and {M}eda, {N}. and {V}an de {P}erre, {P}. and {N}eveu, {D}. and {B}anuls, {A}nne-{L}aure and {G}odreuil, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {I}n sub-{S}aharan {A}frica, bovine tuberculosis (b{TB}) is a potential hazard for animals and humans health. {T}he goal of this study was to improve our understanding of b{TB} epidemiology in {B}urkina {F}aso and especially {M}ycobacterium bovis transmission within and between the bovine and human populations. {M}ethodology/principal findings: {T}wenty six {M}. bovis strains were isolated from 101 cattle carcasses with suspected b{TB} lesions during routine meat inspections at the {B}obo {D}ioulasso and {O}uagadougou slaughterhouses. {I}n addition, 7 {M}. bovis strains were isolated from 576 patients with pulmonary tuberculosis. {S}poligotyping, {RDA}f1 deletion and {MIRU}-{VNTR} typing were used for strains genotyping. {T}he isolation of {M}. bovis strains was confirmed by spoligotyping and 12 spoligotype signatures were detected. {T}ogether, the spoligotyping and {MIRU}-{VNTR} data allowed grouping the 33 {M}. bovis isolates in seven clusters including isolates exclusively from cattle (5) or humans (1) or from both (1). {M}oreover, these data (genetic analyses and phenetic tree) showed that the {M}. bovis isolates belonged to the {A}frican 1 ({A}f1) clonal complex (81.8%) and the putative {A}frican 5 ({A}f5) clonal complex (18.2%), in agreement with the results of {RDA}f1 deletion typing. {C}onclusions/{S}ignificance: {T}his is the first detailed molecular characterization of {M}. bovis strains from humans and cattle in {B}urkina {F}aso. {T}he distribution of the two {A}f1 and putative {A}f5 clonal complexes is comparable to what has been reported in neighbouring countries. {F}urthermore, the strain genetic profiles suggest that {M}. bovis circulates across the borders and that the {B}urkina {F}aso strains originate from different countries, but have a country-specific evolution. {T}he genetic characterization suggests that, currently, {M}. bovis transmission occurs mainly between cattle, occasionally between cattle and humans and potentially between humans. {T}his study emphasizes the b{TB} risk in cattle but also in humans and the difficulty to set up proper disease control strategies in {B}urkina {F}aso.},
  keywords = {{BURKINA} {FASO}},
  booktitle = {},
  journal = {{P}lo{S} {N}eglected {T}ropical {D}iseases},
  volume = {8},
  numero = {10},
  pages = {e3142 [8 ]},
  ISSN = {1935-2735},
  year = {2014},
  DOI = {10.1371/journal.pntd.0003142},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062711},
}