@article{fdi:010062710,
  title = {{I}nterplay between {P}lasmodium infection and resistance to insecticides in vector mosquitoes},
  author = {{A}lout, {H}. and {Y}ameogo, {B}. and {D}jogb{\'e}nou, {L}. {S}. and {C}handre, {F}abrice and {D}abir{\'e}, {R}. {K}. and {C}orbel, {V}incent and {C}ohuet, {A}nna},
  editor = {},
  language = {{ENG}},
  abstract = {{D}espite its epidemiological importance, the impact of insecticide resistance on vector-parasite interactions and malaria transmission is poorly understood. {H}ere, we explored the impact of {P}lasmodium infection on the level of insecticide resistance to dichlorodiphenyltrichloroethane ({DDT}) in field-caught {A}nopheles gambiae sensu stricto homozygous for the kdr mutation. {R}esults showed that kdr homozygous mosquitoes that fed on infectious blood were more susceptible to {DDT} than mosquitoes that fed on noninfectious blood during both ookinete development (day 1 after the blood meal) and oocyst maturation (day 7 after the blood meal) but not during sporozoite invasion of the salivary glands. {P}lasmodium falciparum infection seemed to impose a fitness cost on mosquitoes by reducing the ability of kdr homozygous {A}. gambiae sensu stricto to survive exposure to {DDT}. {T}hese results suggest an interaction between {P}lasmodium infection and the insecticide susceptibility of mosquitoes carrying insecticide-resistant alleles. {W}e discuss this finding in relation to vector control efficacy.},
  keywords = {malaria ; cost of infection ; {A}nopheles gambiae ; insecticide exposure ; kdr ; insecticide resistance ; {P}lasmodium falciparum ; {BURKINA} {FASO}},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {210},
  numero = {9},
  pages = {1464--1470},
  ISSN = {0022-1899},
  year = {2014},
  DOI = {10.1093/infdis/jiu276},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062710},
}