%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Mediannikov, Oleg
%A Socolovschi, C.
%A Million, M.
%A Sokhna, Cheikh
%A Bassene, H.
%A Diatta, G.
%A Fenollar, F.
%A Raoult, Didier
%T Molecular identification of pathogenic bacteria in eschars from acute febrile patients, Senegal
%D 2014
%L fdi:010062677
%G ENG
%J American Journal of Tropical Medicine and Hygiene
%@ 0002-9637
%K SENEGAL
%M ISI:000344447800027
%N 5
%P 1015-1019
%R 10.4269/ajtmh.13-0629
%U https://www.documentation.ird.fr/hor/fdi:010062677
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010062677.pdf
%V 91
%W Horizon (IRD)
%X Fever caused by Rickettsia fells was recently shown to play an important role in infectious diseases morbidity in sub-Saharan Africa. We collected 68 cotton swabs from fever-associated eschars in four different regions of Senegal. In 5 of 68 eschar samples (7.4%), we have identified DNA from R. felis. In 49 of 68 eschar samples (72.1%), we have identified DNA from Staphylococcus aureus. In 35 of 68 eschar samples (51.5%), we have identified DNA from Streptococcus pyogenes, and in 4 of 68 eschar samples (5.9%), we have identified DNA from Streptococcus pneumoniae. In 34 cases, S. aureus was found together with S. pyogenes. DNA from R. fells was also found in swabs from the skin of the healthy Senegalese villagers (3 of 60; 5%) but not French urbanites. The presence of S. aureus and S. pyogenes was significantly associated with the presence of eschars in febrile patients compared with the healthy skin from the control group. Finally, we confirmed that Senegal is an endemic region for R. fells, which is found in both eschars and healthy skin swabs.
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