Publications des scientifiques de l'IRD

Mediannikov Oleg, Socolovschi C., Million M., Sokhna Cheikh, Bassene H., Diatta G., Fenollar F., Raoult Didier. (2014). Molecular identification of pathogenic bacteria in eschars from acute febrile patients, Senegal. American Journal of Tropical Medicine and Hygiene, 91 (5), p. 1015-1019. ISSN 0002-9637.

Titre du document
Molecular identification of pathogenic bacteria in eschars from acute febrile patients, Senegal
Année de publication
2014
Type de document
Article référencé dans le Web of Science WOS:000344447800027
Auteurs
Mediannikov Oleg, Socolovschi C., Million M., Sokhna Cheikh, Bassene H., Diatta G., Fenollar F., Raoult Didier
Source
American Journal of Tropical Medicine and Hygiene, 2014, 91 (5), p. 1015-1019 ISSN 0002-9637
Fever caused by Rickettsia fells was recently shown to play an important role in infectious diseases morbidity in sub-Saharan Africa. We collected 68 cotton swabs from fever-associated eschars in four different regions of Senegal. In 5 of 68 eschar samples (7.4%), we have identified DNA from R. felis. In 49 of 68 eschar samples (72.1%), we have identified DNA from Staphylococcus aureus. In 35 of 68 eschar samples (51.5%), we have identified DNA from Streptococcus pyogenes, and in 4 of 68 eschar samples (5.9%), we have identified DNA from Streptococcus pneumoniae. In 34 cases, S. aureus was found together with S. pyogenes. DNA from R. fells was also found in swabs from the skin of the healthy Senegalese villagers (3 of 60; 5%) but not French urbanites. The presence of S. aureus and S. pyogenes was significantly associated with the presence of eschars in febrile patients compared with the healthy skin from the control group. Finally, we confirmed that Senegal is an endemic region for R. fells, which is found in both eschars and healthy skin swabs.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Santé : généralités [050] ; Entomologie médicale / Parasitologie / Virologie [052] ; Biotechnologies [084]
Description Géographique
SENEGAL
Localisation
Fonds IRD [F B010062677]
Identifiant IRD
fdi:010062677
Contact