@article{fdi:010062607,
  title = {{S}ynthesis, structures, and selective toxicity to cancer cells of gold({I}) complexes involving {N}-heterocyclic carbene ligands},
  author = {{B}oselli, {L}. and {A}der, {I}. and {C}arraz, {M}a{\¨e}lle and {H}emmert, {C}. and {C}uvillier, {O}. and {G}ornitzka, {H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{N}ew gold({I}) complexes containing two 1-[2-(diethylamino)ethyl]imidazolydene ligands have been synthesized and characterized. {T}he {X}-ray structures of two key compounds are presented. {A}ll complexes have been tested for their antiproliferative activities in prostate cancer cell line {PC}-3. {L}ipophilicity ({L}og {P}) has been determined for these complexes. {T}he most active complex has been tested for the cytotoxic activities in five human cancer cell lines and primary endothelial cells. {T}he most active complex demonstrated a potent selectivity for cancer cells.},
  keywords = {{G}old ; {C}arbene ligands ; {C}ancer ; {L}ipophilicity ; {HUVEC}},
  booktitle = {},
  journal = {{E}uropean {J}ournal of {M}edicinal {C}hemistry},
  volume = {85},
  numero = {},
  pages = {87--94},
  ISSN = {0223-5234},
  year = {2014},
  DOI = {10.1016/j.ejmech.2014.07.086},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062607},
}