@article{fdi:010062597,
  title = {{C}ryptosporidium, {G}iardia, {C}ryptococcus, {P}neumocystis genetic variability : cryptic biological species or clonal near-clades ?},
  author = {{T}ibayrenc, {M}ichel and {A}yala, {F}. {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}n abundant literature dealing with the population genetics and taxonomy of {G}iardia duodenalis, {C}ryptosporidium spp., {P}neumocystis spp., and {C}ryptococcus spp., pathogens of high medical and veterinary relevance, has been produced in recent years. {W}e have analyzed these data in the light of new population genetic concepts dealing with predominant clonal evolution ({PCE}) recently proposed by us. {I}n spite of the considerable phylogenetic diversity that exists among these pathogens, we have found striking similarities among them. {T}he two main {PCE} features described by us, namely highly significant linkage disequilibrium and near-clading (stable phylogenetic clustering clouded by occasional recombination), are clearly observed in {C}ryptococcus and {G}iardia, and more limited indication of them is also present in {C}ryptosporidium and {P}neumocystis. {M}oreover, in several cases, these features still obtain when the near-clades that subdivide the species are analyzed separately ("{R}ussian doll pattern"). {L}astly, several sets of data undermine the notion that certain microbes form clonal lineages simply owing to a lack of opportunity to outcross due to low transmission rates leading to lack of multiclonal infections ("starving sex hypothesis"). {W}e propose that the divergent taxonomic and population genetic inferences advanced by various authors about these pathogens may not correspond to true evolutionary differences and could be, rather, the reflection of idiosyncratic practices among compartmentalized scientific communities. {T}he {PCE} model provides an opportunity to revise the taxonomy and applied research dealing with these pathogens and others, such as viruses, bacteria, parasitic protozoa, and fungi.},
  keywords = {},
  booktitle = {},
  journal = {{P}los {P}athogens},
  volume = {10},
  numero = {4},
  pages = {art. e1003908 [6 ]},
  ISSN = {1553-7366},
  year = {2014},
  DOI = {10.1371/journal.ppat.1003908},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062597},
}