@article{fdi:010062587,
  title = {{T}hermal stress triggers broad {P}ocillopora damicornis transcriptomic remodeling, while {V}ibrio coralliilyticus infection induces a more targeted immuno-suppression response},
  author = {{V}idal-{D}upiol, {J}. and {D}heilly, {N}. {M}. and {R}ondon, {R}. and {G}runau, {C}. and {C}osseau, {C}. and {S}mith, {K}. {M}. and {F}reitag, {M}. and {A}djeroud, {M}ehdi and {M}itta, {G}.},
  editor = {},
  language = {{ENG}},
  abstract = {{G}lobal change and its associated temperature increase has directly or indirectly changed the distributions of hosts and pathogens, and has affected host immunity, pathogen virulence and growth rates. {T}his has resulted in increased disease in natural plant and animal populations worldwide, including scleractinian corals. {W}hile the effects of temperature increase on immunity and pathogen virulence have been clearly identified, their interaction, synergy and relative weight during pathogenesis remain poorly documented. {W}e investigated these phenomena in the interaction between the coral {P}ocillopora damicornis and the bacterium {V}ibrio coralliilyticus, for which the infection process is temperature-dependent. {W}e developed an experimental model that enabled unraveling the effects of thermal stress, and virulence vs. non-virulence of the bacterium. {T}he physiological impacts of various treatments were quantified at the transcriptome level using a combination of {RNA} sequencing and targeted approaches. {T}he results showed that thermal stress triggered a general weakening of the coral, making it more prone to infection, non-virulent bacterium induced an 'efficient' immune response, whereas virulent bacterium caused immuno-suppression in its host.},
  keywords = {{OCEAN} {INDIEN} ; {OCEAN} {PACIFIQUE} ; {INDONESIE}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {9},
  numero = {9},
  pages = {art. e107672 [15 ]},
  ISSN = {1932-6203},
  year = {2014},
  DOI = {10.1371/journal.pone.0107672},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062587},
}