@article{fdi:010062567,
  title = {{T}ranscriptomics reveal several gene expression patterns in the piezophile {D}esulfovibrio hydrothermalis in response to hydrostatic pressure},
  author = {{A}mrani, {A}. and {B}ergon, {A}. and {H}olota, {H}. and {T}amburini, {C}. and {G}arel, {M}. and {O}llivier, {B}ernard and {I}mbert, {J}. and {D}olla, {A}. and {P}radel, {N}athalie},
  editor = {},
  language = {{ENG}},
  abstract = {{RNA}-seq was used to study the response of {D}esulfovibrio hydrothermalis, isolated from a deep-sea hydrothermal chimney on the {E}ast-{P}acific {R}ise at a depth of 2,600 m, to various hydrostatic pressure growth conditions. {T}he transcriptomic datasets obtained after growth at 26, 10 and 0.1 {MP}a identified only 65 differentially expressed genes that were distributed among four main categories: aromatic amino acid and glutamate metabolisms, energy metabolism, signal transduction, and unknown function. {T}he gene expression patterns suggest that {D}. hydrothermalis uses at least three different adaptation mechanisms, according to a hydrostatic pressure threshold ({HP}t) that was estimated to be above 10 {MP}a. {B}oth glutamate and energy metabolism were found to play crucial roles in these mechanisms. {Q}uantitation of the glutamate levels in cells revealed its accumulation at high hydrostatic pressure, suggesting its role as a piezolyte. {ATP} measurements showed that the energy metabolism of this bacterium is optimized for deep-sea life conditions. {T}his study provides new insights into the molecular mechanisms linked to hydrostatic pressure adaptation in sulfate-reducing bacteria.},
  keywords = {{PACIFIQUE}},
  booktitle = {},
  journal = {{P}los {O}ne},
  volume = {9},
  numero = {9},
  pages = {e106831},
  ISSN = {1932-6203},
  year = {2014},
  DOI = {10.1371/journal.pone.0106831},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062567},
}