%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Kariminia, A.
%A Durier, N.
%A Jourdain, Gonzague
%A Saghayam, S.
%A Do, C. V.
%A Nguyen, L. V.
%A Hansudewechakul, R.
%A Lumbiganon, P.
%A Chokephaibulkit, K.
%A Truong, K. H.
%A Sirisanthana, V.
%A Ung, V.
%A Vonthanak, S.
%A Ananworanich, J.
%A Yusoff, N. K. N.
%A Kurniati, N.
%A Razali, K. A.
%A Fong, M. S.
%A Nallusamy, R.
%A Wati, D. K.
%T Weight as predictors of clinical progression and treatment failure : results from the TREAT Asia pediatric HIV observational database
%D 2014
%L fdi:010062508
%G ENG
%J Jaids.Journal of Acquired Immune Deficiency Syndromes
%@ 1525-4135
%K HIV ; cohort ; pediatric ; z score ; disease progression
%K CAMBODGE ; INDE ; INDONESIE ; MALAISIE ; THAILANDE ; VIET NAM
%M ISI:000340727600011
%N 1
%P 71-76
%R 10.1097/QAI.0000000000000227
%U https://www.documentation.ird.fr/hor/fdi:010062508
%> https://www.documentation.ird.fr/intranet/publi/2014/09/010062508.pdf
%V 67
%W Horizon (IRD)
%X Objective: To evaluate the value of time-updated weight and height in predicting clinical progression, and immunological and virological failure in children receiving combination antiretroviral therapy (cART). Methods: We used Cox regression to analyze data of a cohort of Asian children. Results: A total of 2608 children were included; median age at cART was 5.7 years. Time-updated weight for age z score, 23 was associated with mortality (P < 0.001) independent of CD4% and < -2 was associated with immunological failure (P <= 0.03) independent of age at cART. Conclusions: Weight monitoring provides useful data to inform clinical management of children on cART in resource-limited settings.
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