@article{fdi:010062467,
  title = {{E}xposure to disinfectants (soap or hydrogen peroxide) increases tolerance to permethrin in {A}nopheles gambiae populations from the city of {Y}aounde, {C}ameroon},
  author = {{A}ntonio-{N}kondjio, {C}. and {Y}oumsi-{G}oupeyou, {M}. and {K}opya, {E}. and {T}ene-{F}ossog, {B}. and {N}jiokou, {F}. and {C}ostantini, {C}arlo and {A}wono-{A}mbene, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {T}he rapid expansion of insecticide resistance is limiting the efficiency of malaria vector control interventions. {H}owever, current knowledge of factors inducing pyrethroid resistance remains incomplete. {I}n the present study, the role of selection at the larval stage by disinfectants, such as soap and hydrogen peroxide ({H}2{O}2), on adult mosquito resistance to permethrin was investigated. {M}ethods: {F}ield {A}nopheles gambiae sensu lato larvae, were exposed to variable concentrations of soap and {H}2{O}2. {L}arvae surviving to acute toxicity assays after 24 hours were reared to the adult stage and exposed to permethrin. {T}he susceptibility level of adults was compared to the untreated control group. {T}he effect of soap or hydrogen peroxide selection on the length of larval development and emergence rate was assessed. {R}esult: {L}arval bioassays analysis showed a more acute effect of hydrogen peroxide on mosquito larvae compared to soap. {T}he regression lines describing the dose mortality profile showed higher mean and variance to hydrogen peroxide than to soap. {T}he duration of larval development (<5 days) and adults emergence rates (1 to 77%) were shorter and lower compare to control. {A}nopheles gambiae s.l. larvae surviving to selection with either soap or hydrogen peroxide or both, produced adults who were up to eight-times more resistant to permethrin than mosquitoes from the untreated control group. {C}onclusion: {T}he present study shows that selective pressure exerted by non-insecticidal compounds such as soap and hydrogen peroxide affect {A}n. gambiae s.l. tolerance to pyrethroids. {T}his requires further studies with regard to the adaptation of {A}n. gambiae s.l. to polluted habitats across sub-{S}aharan {A}frica cities.},
  keywords = {{A}nopheles gambiae ; {S}oap ; {H}ydrogen peroxide ; {P}ermethrin tolerance ; {S}election ; {CAMEROUN}},
  booktitle = {},
  journal = {{M}alaria {J}ournal},
  volume = {13},
  numero = {},
  pages = {art. 296 [7 ]},
  ISSN = {1475-2875},
  year = {2014},
  DOI = {10.1186/1475-2875-13-296},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062467},
}