@article{fdi:010062371, title = {{G}enome sequence of the tsetse fly ({G}lossina morsitans) : vector of {A}frican trypanosomiasis}, author = {{W}atanabe, {J}. and {H}attori, {M}. and {B}erriman, {M}. and {L}ehane, {M}. {J}. and {H}all, {N}. and {S}olano, {P}hilippe and {A}ksoy, {S}. and {H}ide, {W}. and {T}oure, {Y}. and {A}ttardo, {G}. {M}. and {D}arby, {A}. {C}. and {T}oyoda, {A}. and {H}ertz-{F}owler, {C}. and {L}arkin, {D}. {M}. and {C}otton, {J}. {A}. and {S}anders, {M}. {J}. and {S}wain, {M}. {T}. and {Q}uail, {M}. {A}. and {I}noue, {N}. and {R}avel, {S}ophie and et al.}, editor = {}, language = {{ENG}}, abstract = {{T}setse flies are the sole vectors of human {A}frican trypanosomiasis throughout sub-{S}aharan {A}frica. {B}oth sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. {N}otable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. {H}ere, we describe the sequence and annotation of the 366-megabase {G}lossina morsitans morsitans genome. {A}nalysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial ({W}olbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/ chemosensory associated genes. {T}hese genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.}, keywords = {{AFRIQUE} {SUBSAHARIENNE}}, booktitle = {}, journal = {{S}cience}, volume = {344}, numero = {6182}, pages = {380--386}, ISSN = {0036-8075}, year = {2014}, DOI = {10.1126/science.1249656}, URL = {https://www.documentation.ird.fr/hor/fdi:010062371}, }