Publications des scientifiques de l'IRD

Watanabe J., Hattori M., Berriman M., Lehane M. J., Hall N., Solano Philippe, Aksoy S., Hide W., Toure Y., Attardo G. M., Darby A. C., Toyoda A., Hertz-Fowler C., Larkin D. M., Cotton J. A., Sanders M. J., Swain M. T., Quail M. A., Inoue N., Ravel Sophie, et al. (2014). Genome sequence of the tsetse fly (Glossina morsitans) : vector of African trypanosomiasis. Science, 344 (6182), p. 380-386. ISSN 0036-8075.

Titre du document
Genome sequence of the tsetse fly (Glossina morsitans) : vector of African trypanosomiasis
Année de publication
2014
Type de document
Article référencé dans le Web of Science WOS:000334867800033
Auteurs
Watanabe J., Hattori M., Berriman M., Lehane M. J., Hall N., Solano Philippe, Aksoy S., Hide W., Toure Y., Attardo G. M., Darby A. C., Toyoda A., Hertz-Fowler C., Larkin D. M., Cotton J. A., Sanders M. J., Swain M. T., Quail M. A., Inoue N., Ravel Sophie, et al.
Source
Science, 2014, 344 (6182), p. 380-386 ISSN 0036-8075
Tsetse flies are the sole vectors of human African trypanosomiasis throughout sub-Saharan Africa. Both sexes of adult tsetse feed exclusively on blood and contribute to disease transmission. Notable differences between tsetse and other disease vectors include obligate microbial symbioses, viviparous reproduction, and lactation. Here, we describe the sequence and annotation of the 366-megabase Glossina morsitans morsitans genome. Analysis of the genome and the 12,308 predicted protein-encoding genes led to multiple discoveries, including chromosomal integrations of bacterial (Wolbachia) genome sequences, a family of lactation-specific proteins, reduced complement of host pathogen recognition proteins, and reduced olfaction/ chemosensory associated genes. These genome data provide a foundation for research into trypanosomiasis prevention and yield important insights with broad implications for multiple aspects of tsetse biology.
Plan de classement
Sciences fondamentales / Techniques d'analyse et de recherche [020] ; Entomologie médicale / Parasitologie / Virologie [052]
Description Géographique
AFRIQUE SUBSAHARIENNE
Localisation
Fonds IRD [F B010062371]
Identifiant IRD
fdi:010062371
Contact