@article{fdi:010062329,
  title = {{V}iral etiology and seasonality of influenza-like illness in {G}abon, {M}arch 2010 to {J}une 2011},
  author = {{L}ekana-{D}ouki, {S}. {E}. and {N}koghe, {D}. and {D}rosten, {C}. and {N}goungou, {E}. {B}. and {D}rexler, {J}. {F}. and {L}eroy, {E}ric},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {S}urveillance of influenza-like illness ({ILI}) in {C}entral {A}frica began only recently, and few data are therefore available on the circulation of influenza virus and other respiratory viruses. {I}n {G}abon, a {C}entral {A}frican country, we established a surveillance network in four major towns in order to analyze cases of {ILI} among patients who visited health centers between {M}arch 2010 and {J}une 2011, and to determine the viral etiology. {M}ethods: {N}asal swabs were sent for analysis to the {C}entre {I}nternational de {R}echerches {M}edicales de {F}ranceville, where they were screened for 17 respiratory viruses in a multiplex real-time reverse transcription polymerase chain reaction for all pathogens according the following pairs: adenovirus/parainfluenza virus 4, respiratory syncytial virus/human metapneumovirus, parainfluenza virus 1/parainfluenza virus 2, pandemic influenza virus {A}/seasonal influenza virus {A} ({H}1{N}1, {H}3{N}2)/seasonal influenza virus {B}, human coronaviruses 229{E}/{OC}43, human coronaviruses {NL}63/{HKU}1, rhinovirus/human parechovirus, and enterovirus/parainfluenza virus 3. {R}esults: {W}e analyzed a total of 1041 specimens, of which 639 (61%) were positive for at least one virus. {T}hree-quarters of the patients were children under five years old. {W}e therefore focused on this age group, in which 68.1% of patients were positive for at least one virus. {T}he most common viruses were adenoviruses (17.5%), followed by parainfluenza viruses ({PIV}s) 1-4 (16.8%), enteroviruses ({EV}) (14.7%), respiratory syncytial virus ({RSV}) (13.5%), and influenza virus (11.9%). {T}he prevalence of some viruses was subject to geographic and seasonal variations. {O}ne-third of positive samples contained more than one virus. {C}onclusions: {L}ike most studies in the world, the virus {PIV}s, {EV}, {RSV}, {I}nfluenza virus, {HRV} were predominant among children under five years old in {G}abon. {A}n exception is made for adenoviruses which have a high prevalence in our study. {H}owever adenoviruses can be detected in asymptomatic persons. {T}hese finding gave a better knowledge of the circulation and the seasonality of the viruses involved in {ILI} in {G}abon.},
  keywords = {{G}abon ; {S}urveillance network ; {I}nfluenza-like illness ; {V}iruses ; {S}easonality ; {GABON}},
  booktitle = {},
  journal = {{B}mc {I}nfectious {D}iseases},
  volume = {14},
  numero = {},
  pages = {art. 373},
  ISSN = {1471-2334},
  year = {2014},
  DOI = {10.1186/1471-2334-14-373},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062329},
}