@article{fdi:010062293,
  title = {{D}iversification of an emerging pathogen in a biodiversity hotspot : {L}eptospira in endemic small mammals of {M}adagascar},
  author = {{D}ietrich, {M}. and {W}ilkinson, {D}. {A}. and {S}oarimalala, {V}. and {G}oodman, {S}. {M}. and {D}ellagi, {K}oussay and {T}ortosa, {P}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}iodiversity hotspots and associated endemism are ideal systems for the study of parasite diversity within host communities. {H}ere, we investigated the ecological and evolutionary forces acting on the diversification of an emerging bacterial pathogen, {L}eptospira spp., in communities of endemic {M}alagasy small mammals. {W}e determined the infection rate with pathogenic {L}eptospira in 20 species of sympatric rodents (subfamily {N}esomyinae) and tenrecids (family {T}enrecidae) at two eastern humid forest localities. {A} multilocus genotyping analysis allowed the characterization of bacterial diversity within small mammals and gave insights into their genetic relationships with {L}eptospira infecting endemic {M}alagasy bats (family {M}iniopteridae and {V}espertilionidae). {W}e report for the first time the presence of pathogenic {L}eptospira in {M}alagasy endemic small mammals, with an overall prevalence of 13%. {I}n addition, these hosts harbour species of {L}eptospira ({L}.kirschneri, {L}.borgpetersenii and {L}.borgpetersenii group {B}) which are different from those reported in introduced rats ({L}.interrogans) on {M}adagascar. {T}he diversification of {L}eptospira on {M}adagascar can be traced millions of years into evolutionary history, resulting in the divergence of endemic lineages and strong host specificity. {T}hese observations are discussed in relation to the relative roles of endemic vs. introduced mammal species in the evolution and epidemiology of {L}eptospira on {M}adagascar, specifically how biodiversity and biogeographical processes can shape community ecology of an emerging pathogen and lead to its diversification within native animal communities.},
  keywords = {{L}eptospira borgpetersenii ; {L}eptospira interrogans ; {M}iniopteridae ; multilocus analysis ; {N}esomyinae ; {T}enrecidae ; {V}espertilionidae ; {MADAGASCAR}},
  booktitle = {},
  journal = {{M}olecular {E}cology},
  volume = {23},
  numero = {11},
  pages = {2783--2796},
  ISSN = {0962-1083},
  year = {2014},
  DOI = {10.1111/mec.12777},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062293},
}