@article{fdi:010062070, title = {{C}hiral signature of venlafaxine as a marker of biological attenuation processes}, author = {{L}i, {Z}. and {G}omez, {E}. and {F}enet, {H}. and {C}hiron, {S}erge}, editor = {}, language = {{ENG}}, abstract = {{T}he chiral signature of the antidepressant venlafaxine was used in this study to gain insight into biological attenuation processes and to differentiate abiotic and biotic transformation processes in water. {L}aboratory scale experiments revealed that sorption and phototransformation processes were not enantioselective while venlafaxine was enantioselectively biotransformed into {O}-desmethylvenlafaxine. {T}he enantiomeric fraction ({EF}) variations of venlafaxine appeared to be proportional to its microbial fractional conversion. {E}nantioselective biotransformation of venlafaxine was also investigated in a eutrophic {F}rench river. {V}enlafaxine was found to be racemic at the output of the main wastewater treatment plant discharging into the river, independently of the sampling date during the year. {A}n analysis of {EF} variations might provide evidence of biodegradation along a 30 km river stretch.}, keywords = {{V}enlafaxine ; {C}hiral signature ; {W}ater ; {B}iodegradation ; {FRANCE}}, booktitle = {}, journal = {{C}hemosphere}, volume = {90}, numero = {6}, pages = {1933--1938}, ISSN = {0045-6535}, year = {2013}, DOI = {10.1016/j.chemosphere.2012.10.033}, URL = {https://www.documentation.ird.fr/hor/fdi:010062070}, }