@article{fdi:010062059,
  title = {{M}etabolomic and ecdysteroid variations in {A}nopheles gambiae s. l. mosquitoes exposed to the stressful conditions of the dry season in {B}urkina {F}aso, {W}est {A}frica},
  author = {{M}amai, {W}. and {M}ouline, {K}arine and {B}lais, {C}. and {L}arvor, {V}. and {D}abir{\'e}, {K}. {R}. and {O}uedraogo, {G}. {A}. and {S}imard, {F}r{\'e}d{\'e}ric and {R}enault, {D}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}his study explored the metabolic adjustments prompted by a switch between the rainy and dry season conditions in the {A}frican malaria mosquitoes {A}nopheles gambiae ({M} and {S} molecular forms) and {A}nopheles arabiensis. {M}osquitoes were reared in contrasted experimental conditions reflecting environmental variation in {B}urkina {F}aso. {T}hirty-five metabolites (including sugars, polyols, and amino acids) were monitored in newly emerged males and females, and their ecdysteroid titers were determined. {M}etabolomic signatures were remarkably similar across species, when specimens of same age and sex were reared under identical experimental conditions. {I}n males and females, amino acids (including glycine, leucine, phenylanine, serine, threonine, and valine) were accumulated in 1-h-old mosquitoes, then decreased 24 h after emergence, probably reflecting adult maturation and the amino acid-consuming process of cuticle sclerotisation. {I}n turn, elevated amounts of alanine and proline in 24-h-old mosquitoes may assist the development of flight ability. {L}ower concentration of tricarboxylic acid cycle intermediates and isoleucine characterized older females reared under dry season conditions, suggesting metabolic and reproduction depression. {I}n all cases, ecdysteroid concentration was much higher in males than in females, with significant seasonal variation in males. {T}his might reflect a unique role of these hormones in shaping reproductive strategies and population demography in the {A}n. gambiae s.l. species complex, further contributing to local adaptation in a highly fluctuating environment.},
  keywords = {{BURKINA} {FASO}},
  booktitle = {},
  journal = {{P}hysiological and {B}iochemical {Z}oology},
  volume = {87},
  numero = {3},
  pages = {486--497},
  ISSN = {1522-2152},
  year = {2014},
  DOI = {10.1086/675697},
  URL = {https://www.documentation.ird.fr/hor/fdi:010062059},
}