@article{fdi:010062027, title = {{V}irus nomenclature below the species level : a standardized nomenclature for filovirus strains and variants rescued from c{DNA}}, author = {{K}uhn, {J}. {H}. and {B}ao, {Y}. {M}. and {B}avari, {S}. and {B}ecker, {S}. and {B}radfute, {S}. and {B}rauburger, {K}. and {B}rister, {J}. {R}. and {B}ukreyev, {A}. {A}. and {C}ai, {Y}. {Y}. and {C}handran, {K}. and {D}avey, {R}. {A}. and {D}olnik, {O}. and {D}ye, {J}. {M}. and {E}nterlein, {S}. and {G}onzalez, {J}ean-{P}aul and {F}ormenty, {P}. and {F}reiberg, {A}. {N}. and {H}ensley, {L}. {E}. and {H}oenen, {T}. and {H}onko, {A}. {N}. and {I}gnatyev, {G}. {M}. and {J}ahrling, {P}. {B}. and {J}ohnson, {K}. {M}. and {K}lenk, {H}. {D}. and {K}obinger, {G}. and {L}ackemeyer, {M}. {G}. and {L}eroy, {E}ric and {L}ever, {M}. {S}. and {M}uhlberger, {E}. and {N}etesov, {S}. {V}. and {O}linger, {G}. {G}. and {P}alacios, {G}. and {P}atterson, {J}. {L}. and {P}aweska, {J}. {T}. and {P}itt, {L}. and {R}adoshitzky, {S}. {R}. and {R}yabchikova, {E}. {I}. and {S}aphire, {E}. {O}. and {S}hestopalov, {A}. {M}. and {S}mither, {S}. {J}. and {S}ullivan, {N}. {J}. and {S}wanepoel, {R}. and {T}akada, {A}. and {T}owner, {J}. {S}. and van der {G}roen, {G}. and {V}olchkov, {V}. {E}. and {V}olchkova, {V}. {A}. and {W}ahl-{J}ensen, {V}. and {W}arren, {T}. {K}. and {W}arfield, {K}. {L}. and {W}eidmann, {M}. and {N}ichol, {S}. {T}.}, editor = {}, language = {{ENG}}, abstract = {{S}pecific alterations (mutations, deletions, insertions) of virus genomes are crucial for the functional characterization of their regulatory elements and their expression products, as well as a prerequisite for the creation of attenuated viruses that could serve as vaccine candidates. {V}irus genome tailoring can be performed either by using traditionally cloned genomes as starting materials, followed by site-directed mutagenesis, or by de novo synthesis of modified virus genomes or parts thereof. {A} systematic nomenclature for such recombinant viruses is necessary to set them apart from wild-type and laboratory-adapted viruses, and to improve communication and collaborations among researchers who may want to use recombinant viruses or create novel viruses based on them. {A} large group of filovirus experts has recently proposed nomenclatures for natural and laboratory animal-adapted filoviruses that aim to simplify the retrieval of sequence data from electronic databases. {H}ere, this work is extended to include nomenclature for filoviruses obtained in the laboratory via reverse genetics systems. {T}he previously developed template for natural filovirus genetic variant naming, < virus name > (< strain >/)< isolation host-suffix >/< country of sampling >/< year of sampling >/< genetic variant designation >-< isolate designation >, is retained, but we propose to adapt the type of information added to each field for c{DNA} clone-derived filoviruses. {F}or instance, the full-length designation of an {E}bola virus {K}ikwit variant rescued from a plasmid developed at the {US} {C}enters for {D}isease {C}ontrol and {P}revention could be akin to "{E}bola virus {H}.sapiens-rec/{COD}/1995/{K}ikwit-abc1" (with the suffix "rec" identifying the recombinant nature of the virus and "abc1" being a placeholder for any meaningful isolate designator). {S}uch a full-length designation should be used in databases and the methods section of publications. {S}hortened designations (such as "{EBOV} {H}.sap/{COD}/95/{K}ik-abc1") and abbreviations (such as "{EBOV}/{K}ik-abc1") could be used in the remainder of the text, depending on how critical it is to convey information contained in the full-length name. "{EBOV}" would suffice if only one {EBOV} strain/variant/isolate is addressed.}, keywords = {}, booktitle = {}, journal = {{A}rchives of {V}irology}, volume = {159}, numero = {5}, pages = {1229--1237}, ISSN = {0304-8608}, year = {2014}, DOI = {10.1007/s00705-013-1877-2}, URL = {https://www.documentation.ird.fr/hor/fdi:010062027}, }