@article{fdi:010061892, title = {{H}ow community ecology can improve our understanding of cholera dynamics}, author = {{C}onstantin de {M}agny, {G}uillaume and {H}asan, {N}. {A}. and {R}oche, {B}enjamin}, editor = {}, language = {{ENG}}, abstract = {{U}nderstanding the seasonal emergence and reemergence of cholera is challenging due to the complex dynamics of different protagonists. {T}he abundance of {V}ibrio cholerae, the causative agent of cholera and a natural inhabitant of aquatic environments, fluctuates according to abiotic, and biotic factors. {A}mong the biotic factors, the zooplankton community dynamics has been suggested to play a pivotal role in the survival, persistence, and natural competence of {V} cholerae. {H}owever, factors regulating {V} cholerae population structure and seasonal dynamics are still not fully understood. {I}nvestigation of the temporal shifts and variability in aquatic community composition in relation to the occurrence or abundance of {V} cholerae appears very promising yet remained underexplored. {R}ecent advances in metagenomics, facilitated by high-throughput ultra deep sequencing, have greatly improved our ability for a broader and deeper exploration of microbial communities including an understanding of community structure, function, as well as inter- and intra-specific competitions. {H}ere, we discuss possible areas of research focusing how combination of community ecology and metagenomic approaches could be applied to study the cholera system.}, keywords = {cholera ; ecology ; metagenomics ; genetics ; pathogen}, booktitle = {}, journal = {{F}rontiers in {M}icrobiology}, volume = {5}, numero = {}, pages = {art. 137}, ISSN = {1664-302{X}}, year = {2014}, DOI = {10.3389/fmicb.2014.00137}, URL = {https://www.documentation.ird.fr/hor/fdi:010061892}, }