@article{fdi:010061853,
  title = {{EPR} spectroelectrochemical investigation of guanine radical formation and environment effects},
  author = {{R}ibaut, {C}. and {B}ordeau, {G}. and {P}erio, {P}ierre and {R}eybier, {K}. and {S}artor, {V}. and {R}eynes, {O}. and {F}abre, {P}. {L}. and {C}houini-{L}alanne, {N}.},
  editor = {},
  language = {{ENG}},
  abstract = {{G}uanine radical detection was carried out by a new convenient and efficient method coupling electron paramagnetic resonance spectroscopy and indirect electro-oxidation of guanine in different biological environments, from the free nucleotide to several types of {DNA} substrates. {C}ompared to the widely used photoirradiation method, this method appeared more selective in the choice of the electrochemical mediator. {C}arried out in presence of a ruthenium mediator and {PBN} as spin trap, this method revealed two types of {EPR} spectra depending of the environment of the guanine radical. {B}oth {EPR} spectra show the trapping of the neutral guanine radical {G}(-{H})(center dot) obtained after fast deprotonation of the radical cation {G}(center dot+). {H}owever, they differ by the atom where the trapped radical is centered. {T}his difference highlights the structural dependency of the environment on the nature of the radical formed. {T}his work gave the evidence of an innovative method to detect in situ the guanine radical.},
  keywords = {},
  booktitle = {},
  journal = {{J}ournal of {P}hysical {C}hemistry {B}},
  volume = {118},
  numero = {9},
  pages = {2360--2365},
  ISSN = {1520-6106},
  year = {2014},
  DOI = {10.1021/jp500952q},
  URL = {https://www.documentation.ird.fr/hor/fdi:010061853},
}