@article{fdi:010061296, title = {{A} recessive resistance to {R}ice yellow mottle virus is associated with a rice homolog of the cpr5 gene, a regulator of active defense mechanisms}, author = {{O}rjuela, {J}ulie and {D}eless, {E}. {F}. {T}. and {K}olade, {O}. and {C}h{\'e}ron, {S}ophie and {G}hesqui{\`e}re, {A}lain and {A}lbar, {L}aurence}, editor = {}, language = {{ENG}}, abstract = {{RYMV}2 is a major recessive resistance gene identified in cultivated {A}frican rice ({O}ryza glaberrima) which confers high resistance to the {R}ice yellow mottle virus ({RYMV}). {W}e mapped {RYMV}2 in an approximately 30-kb interval in which four genes have been annotated. {S}equencing of the candidate region in the resistant {T}og7291 accession revealed a single mutation affecting a predicted gene, as compared with the {RYMV}-susceptible {O}. glaberrima {CG}14 reference sequence. {T}his mutation was found to be a one-base deletion leading to a truncated and probably nonfunctional protein. {I}t affected a gene homologous to the {A}rabidopsis thaliana {CPR}5 gene, known to be a defense mechanism regulator. {O}nly seven {O}. glaberrima accessions showing this deletion were identified in a collection consisting of 417 accessions from three rice species. {A}ll seven accessions were resistant to {RYMV}, which is an additional argument in favor of the involvement of the deletion in resistance. {I}n addition, fine mapping of a resistance quantitative trait locus in {O}. sativa advanced backcrossed lines pinpointed a 151-kb interval containing {RYMV}2, suggesting that allelic variants of the same gene may control both high and partial resistance.}, keywords = {}, booktitle = {}, journal = {{M}olecular {P}lant-{M}icrobe {I}nteractions}, volume = {26}, numero = {12}, pages = {1455--1463}, ISSN = {0894-0282}, year = {2013}, DOI = {10.1094/mpmi-05-13-0127-r}, URL = {https://www.documentation.ird.fr/hor/fdi:010061296}, }